Morphological imaging and T2 and T2* mapping of hip cartilage at 7 Tesla MRI under the influence of intravenous gadolinium.
Objectives: To investigate the influence of intravenous gadolinium on cartilage T2 and T2* relaxation times and on morphological image quality at 7-T hip MRI.Methods: Hips of 11 healthy volunteers were examined at 7 T. Multi-echo sequences for T2 and T2* mapping, 3D T1 volumetric interpolated breath...
| Published in: | European Radiology Vol. 26; no. 11; pp. 3923 - 3932 |
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| Main Authors: | , , , , , , , , , , |
| Format: | Journal Article |
| Published: |
Springer Nature
Nov2016
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=118554742&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 118554742 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Nov2016 vid: 26 iid: 11 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 118554742 118554742 NLM26873493 10.1007/s00330-016-4247-0 NLM26873493 118554742 ppf: 3923 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Morphological imaging and T2 and T2* mapping of hip cartilage at 7 Tesla MRI under the influence of intravenous gadolinium. aug: au: Lazik-Palm, Andrea Kraff, Oliver Geis, Christina Johst, Sören Goebel, Juliane Ladd, Mark Quick, Harald Theysohn, Jens Ladd, Mark E Quick, Harald H Theysohn, Jens M affil: Department of Diagnostic and Interventional Radiology and Neuroradiology , University Hospital Essen , Hufelandstr. 55 45147 Essen Germany sug: subj: Cartilage, Articular Anatomy and Histology Contrast Media Administration and Dosage Hip Joint Anatomy and Histology Acetabulum Anatomy and Histology Research Subjects Female Cartilage, Articular Drug Effects Adult Magnetic Resonance Imaging Methods Male Administration, Intravenous Ferrans and Powers Quality of Life Index Adult: 19-44 years Female Male ab: Objectives: To investigate the influence of intravenous gadolinium on cartilage T2 and T2* relaxation times and on morphological image quality at 7-T hip MRI.Methods: Hips of 11 healthy volunteers were examined at 7 T. Multi-echo sequences for T2 and T2* mapping, 3D T1 volumetric interpolated breath-hold examination (VIBE) and double-echo steady-state (DESS) sequences were acquired before and after intravenous application of gadolinium according to a delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) protocol. Cartilage relaxation times were measured in both scans. Morphological sequences were assessed quantitatively using contrast ratios and qualitatively using a 4-point Likert scale. Student's t-test, Pearson's correlation (ρ) and Wilcoxon sign-rank test were used for statistical comparisons.Results: Pre- and post-contrast T2 and T2* values were highly correlated (T2: acetabular: ρ = 0.76, femoral: ρ = 0.77; T2*: acetabular: ρ = 0.80, femoral: ρ = 0.72). Gadolinium enhanced contrasts between cartilage and joint fluid in DESS and T1 VIBE according to the qualitative (p = 0.01) and quantitative (p < 0.001) analysis. The delineation of acetabular and femoral cartilage and the labrum predominantly improved with gadolinium.Conclusions: Gadolinium showed no relevant influence on T2 or T2* relaxation times and improved morphological image quality at 7 T. Therefore, morphological and quantitative sequences including dGEMRIC can be conducted in a one-stop-shop examination.Key Points: • Hip cartilage T2 values correlate highly before and after gadolinium at 7 T • Hip cartilage T2* values correlate highly before and after enhancement at 7 T • Morphological hip cartilage imaging benefits from intravenous gadolinium at 7 T • The delineation of acetabular and femoral cartilage can be improved by gadolinium • Morphological and quantitative sequences including dGEMRIC can be combined as a one-stop-shop examination. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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