No Association Between Unintentional Head Injuries and Early-Life Exposure to Tetrachloroethylene (PCE)-Contaminated Drinking Water.

Objective: Because of emerging evidence that early-life exposure to the solvent tetrachloroethylene (PCE) has long-lasting neurological consequences, we examined the risk of unintentional head injuries following prenatal and childhood exposure to PCE-contaminated drinking water. Methods: Participant...

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Publicado en:Journal of Occupational & Environmental Medicine Vol. 58; no. 10; pp. 1040 - 1046
Autores principales: Aschengrau, Ann, Gallagher, Lisa G., Winter, Michael R., Vieira, Veronica M., Janulewicz, Patricia A., Webster, Thomas F., Ozonoff, David M.
Formato: research tables/charts Journal Article
Publicado: Lippincott Williams & Wilkins Oct2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2016
      vid: 58
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      pub: Lippincott Williams & Wilkins
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        atl: No Association Between Unintentional Head Injuries and Early-Life Exposure to Tetrachloroethylene (PCE)-Contaminated Drinking Water.
      aug:
        au:
          Aschengrau, Ann
          Gallagher, Lisa G.
          Winter, Michael R.
          Vieira, Veronica M.
          Janulewicz, Patricia A.
          Webster, Thomas F.
          Ozonoff, David M.
        affil: Department of Epidemiology, Boston University School of Public Health, Crosstown, Boston, Massachusetts
      sug:
        subj:
          Solvents Adverse Effects
          Head Injuries Risk Factors
          Environmental Exposure In Utero
          Environmental Exposure In Infancy and Childhood
          Human
          Retrospective Design
          Questionnaires
          Neurologic Manifestations
          Neurotoxicity Syndromes
          Water Pollution
          Fetus
          Child
          Adult
          Fetus, conception to birth
          Child: 6-12 years
          Adult: 19-44 years
      ab: Objective: Because of emerging evidence that early-life exposure to the solvent tetrachloroethylene (PCE) has long-lasting neurological consequences, we examined the risk of unintentional head injuries following prenatal and childhood exposure to PCE-contaminated drinking water. Methods: Participants provided information on head injuries and other relevant characteristics in a self-administered questionnaire. Exposure to PCE was modeled using a leaching and transport algorithm set in water system modeling software. Results: We did not observe any evidence of an increased risk of any type of head injury among exposed participants. Conclusions: PCE is a widespread water pollutant. Thus, documenting possible health effects of early-life exposure is vital for ensuring that drinking water regulations adequately protect vulnerable populations.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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