Catheter Ablation for Atrial Arrhythmias in Patients With Cardiac Amyloidosis.
Catheter Ablation for Atrial Arrhythmias in Patients With CA Background Cardiac amyloidosis (CA) is associated with increased atrial arrhythmias risk. The efficacy/safety of catheter-based ablation therapy in patients with CA has not been adequately assessed. Methods and Results All diagnosed CA pat...
| Publicado en: | Journal of Cardiovascular Electrophysiology Vol. 27; no. 10; pp. 1167 - 1174 |
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| Autores principales: | , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Oct2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=118833276&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 118833276 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10453873 GSB jtl: Journal of Cardiovascular Electrophysiology issn: 10453873 maglogo: Y pubinfo: dt: Oct2016 vid: 27 iid: 10 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 118833276 118833276 118833276 10.1111/jce.13046 118833276 ppf: 1167 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Catheter Ablation for Atrial Arrhythmias in Patients With Cardiac Amyloidosis. aug: au: TAN, NICHOLAS Y. MOHSIN, YOUSEF HODGE, DAVID O. LACY, MARTHA Q. PACKER, DOUGLAS L. DISPENZIERI, ANGELA GROGAN, MARTHA ASIRVATHAM, SAMUEL J. MADHAVAN, MALINI McLEOD, CHRISTOPHER J. affil: Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester Minnesota sug: subj: Amyloidosis, Cardiac Complications Catheter Ablation Arrhythmia, Atrial Therapy Treatment Outcomes Recurrence Serum Albumin Blood Human Female Male Chi Square Test Kaplan-Meier Estimator P-Value Retrospective Design Inpatients Academic Medical Centers United States United States Arrhythmia, Atrial Symptoms Arrhythmia, Atrial Mortality Middle Age Aged Middle Aged: 45-64 years Aged: 65+ years Female Male ab: Catheter Ablation for Atrial Arrhythmias in Patients With CA Background Cardiac amyloidosis (CA) is associated with increased atrial arrhythmias risk. The efficacy/safety of catheter-based ablation therapy in patients with CA has not been adequately assessed. Methods and Results All diagnosed CA patients who underwent atrial arrhythmia ablation therapy from 1995 to 2015 were reviewed. Arrhythmia recurrence, NYHA symptoms, and mortality were recorded. A total of 26 patients with CA and atrial arrhythmias were included; there were 7 light-chain (AL), 17 wild-type transthyretin (ATTRwt), and 2 mutated transthyretin (ATTRm) amyloidosis patients in total. Of which 13 underwent atrial arrhythmia ablation (CA-A) and 13 underwent AV nodal ablation (CA-AVN). In the CA-A group, there were: 3 with atrial fibrillation (AF); 6 with atrial flutter (AFL); 2 with AF/AFL; and 2 with atrial tachycardia (AT). One-year and 3-year recurrence-free survival were 75% and 60%, respectively. NYHA symptom improvement 6 months postablation was observed in both CA-A and CA-AVN groups: 7/10 (70%) and 4/8 (50%), respectively. Eleven patients with CA died (8 in CA-AVN group vs. 3 in CA-A group). Conclusions Catheter-based ablation for patients with CA appears to provide important symptomatic relief. However, mortality from the underlying disease remains a significant issue for the amyloid light-chain subtype. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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