Nonnegative matrix factorization and sparse representation for the automated detection of periodic limb movements in sleep.

Stroke is a leading cause of death and disability in adults, and incurs a significant economic burden to society. Periodic limb movements (PLMs) in sleep are repetitive movements involving the great toe, ankle, and hip. Evolving evidence suggests that PLMs may be associated with high blood pressure...

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Published in:Medical & Biological Engineering & Computing Vol. 54; no. 11; pp. 1641 - 1655
Main Authors: Shokrollahi, Mehrnaz, Krishnan, Sridhar, Dopsa, Dustin, Muir, Ryan, Black, Sandra, Swartz, Richard, Murray, Brian, Boulos, Mark, Dopsa, Dustin D, Muir, Ryan T, Black, Sandra E, Swartz, Richard H, Murray, Brian J, Boulos, Mark I
Format: Journal Article
Published: Springer Nature Nov2016
Online Access:View this record in EBSCOhost
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      dt: Nov2016
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      pub: Springer Nature
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          Shokrollahi, Mehrnaz
          Krishnan, Sridhar
          Dopsa, Dustin
          Muir, Ryan
          Black, Sandra
          Swartz, Richard
          Murray, Brian
          Boulos, Mark
          Dopsa, Dustin D
          Muir, Ryan T
          Black, Sandra E
          Swartz, Richard H
          Murray, Brian J
          Boulos, Mark I
        affil: Department of Computer Science, Toronto Rehabilitation Institute , University of Toronto , 555 University Ave Toronto M5G 2A2 Canada
      sug:
        subj:
          Algorithms
          Sleep
          Automation
          Signal Processing, Computer Assisted
          Female
          Male
          Electromyography
          Sleep Stages
          Middle Age
          Stroke Diagnosis
          Time Factors
          Brain Pathology
          Middle Aged: 45-64 years
          Female
          Male
      ab: Stroke is a leading cause of death and disability in adults, and incurs a significant economic burden to society. Periodic limb movements (PLMs) in sleep are repetitive movements involving the great toe, ankle, and hip. Evolving evidence suggests that PLMs may be associated with high blood pressure and stroke, but this relationship remains underexplored. Several issues limit the study of PLMs including the need to manually score them, which is time-consuming and costly. For this reason, we developed a novel automated method for nocturnal PLM detection, which was shown to be correlated with (a) the manually scored PLM index on polysomnography, and (b) white matter hyperintensities on brain imaging, which have been demonstrated to be associated with PLMs. Our proposed algorithm consists of three main stages: (1) representing the signal in the time-frequency plane using time-frequency matrices (TFM), (2) applying K-nonnegative matrix factorization technique to decompose the TFM matrix into its significant components, and (3) applying kernel sparse representation for classification (KSRC) to the decomposed signal. Our approach was applied to a dataset that consisted of 65 subjects who underwent polysomnography. An overall classification of 97 % was achieved for discrimination of the aforementioned signals, demonstrating the potential of the presented method.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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