White Matter Volume Mediates the Relationship Between Self-Efficacy and Mobility in Older Women.

Background/Study Context: With our aging population, understanding determinants of healthy aging is a priority. One essential component of healthy aging is mobility. Although self-efficacy can directly impact mobility in older adults, it is unknown what role brain health may play in this relationshi...

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Published in:Experimental Aging Research Vol. 42; no. 5; pp. 460 - 471
Main Authors: Nagamatsu, Lindsay S., Hsu, Chun Liang, Davis, Jennifer C., Best, John R., Liu-Ambrose, Teresa
Format: research tables/charts Journal Article
Published: Taylor & Francis Ltd Oct-Dec2016
Online Access:View this record in EBSCOhost
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        0361073X
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      dt: Oct-Dec2016
      vid: 42
      iid: 5
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      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
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        10.1080/0361073X.2016.1224657
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        atl: White Matter Volume Mediates the Relationship Between Self-Efficacy and Mobility in Older Women.
      aug:
        au:
          Nagamatsu, Lindsay S.
          Hsu, Chun Liang
          Davis, Jennifer C.
          Best, John R.
          Liu-Ambrose, Teresa
        affil: Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA
      sug:
        subj:
          Brain Anatomy and Histology
          Brain Physiology
          Self-Efficacy In Old Age
          Physical Mobility Psychosocial Factors
          Aging
          Human
          Female
          Aged
          Cross Sectional Studies
          Pilot Studies
          Descriptive Statistics
          Accidental Falls Psychosocial Factors
          Scales
          Psychological Tests
          Depression
          Functional Status
          Aged: 65+ years
          Female
      ab: Background/Study Context: With our aging population, understanding determinants of healthy aging is a priority. One essential component of healthy aging is mobility. Although self-efficacy can directly impact mobility in older adults, it is unknown what role brain health may play in this relationship. Methods: The authors conducted a cross-sectional pilot analysis of community-dwelling women (N = 80, mean age = 69 years) to examine whether brain volume mediates the relationship between falls-related self-efficacy, as measured by the Activities-specific Balance Confidence (ABC) scale, and mobility, as measured by the Timed Up and Go (TUG) test. Age, depression, education, functional comorbidities, and Montreal Cognitive Assessment (MoCA) were included in the model as covariates. Results: The authors report that total white matter volume, specifically, significantly mediates the relationship between self-efficacy and mobility, where higher self-efficacy was associated with greater white matter volume (r =.28), which, in turn, was associated with better mobility (r = −.30). Conclusion: This pilot study extends our understanding of the psychosocial and neurological factors that contribute to mobility and provides insight into effective strategies that may be used to improve functional independence among older adults. Future prospective and intervention studies are required to further elucidate the nature of the relationship between self-efficacy, mobility, and brain health.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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