Brain tumor segmentation from multimodal magnetic resonance images via sparse representation.

Objective: Accurately segmenting and quantifying brain gliomas from magnetic resonance (MR) images remains a challenging task because of the large spatial and structural variability among brain tumors. To develop a fully automatic and accurate brain tumor segmentation algorithm, we present a probabi...

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Publicado en:Artificial Intelligence in Medicine Vol. 73; pp. 1 - 14
Autores principales: Li, Yuhong, Jia, Fucang, Qin, Jing
Formato: research Journal Article
Publicado: Elsevier B.V. Oct2016
Acceso en línea:Ver este registro en EBSCOhost
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        09333657
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      jtl: Artificial Intelligence in Medicine
      issn: 09333657
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      dt: Oct2016
      vid: 73
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      pub: Elsevier B.V.
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        119156112
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        NLM27926377
        119156112
        10.1016/j.artmed.2016.08.004
        NLM27926377
        119156112
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      tig:
        atl: Brain tumor segmentation from multimodal magnetic resonance images via sparse representation.
      aug:
        au:
          Li, Yuhong
          Jia, Fucang
          Qin, Jing
        affil: Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Avenue, Shenzhen University Town, Nanshan District, Shenzhen 518055, China
      sug:
        subj:
          Image Interpretation, Computer Assisted
          Algorithms
          Brain Neoplasms
          Magnetic Resonance Spectroscopy
          Magnetic Resonance Imaging
          Models, Statistical
          Brain
      ab: Objective: Accurately segmenting and quantifying brain gliomas from magnetic resonance (MR) images remains a challenging task because of the large spatial and structural variability among brain tumors. To develop a fully automatic and accurate brain tumor segmentation algorithm, we present a probabilistic model of multimodal MR brain tumor segmentation. This model combines sparse representation and the Markov random field (MRF) to solve the spatial and structural variability problem.Methods: We formulate the tumor segmentation problem as a multi-classification task by labeling each voxel as the maximum posterior probability. We estimate the maximum a posteriori (MAP) probability by introducing the sparse representation into a likelihood probability and a MRF into the prior probability. Considering the MAP as an NP-hard problem, we convert the maximum posterior probability estimation into a minimum energy optimization problem and employ graph cuts to find the solution to the MAP estimation.Results: Our method is evaluated using the Brain Tumor Segmentation Challenge 2013 database (BRATS 2013) and obtained Dice coefficient metric values of 0.85, 0.75, and 0.69 on the high-grade Challenge data set, 0.73, 0.56, and 0.54 on the high-grade Challenge LeaderBoard data set, and 0.84, 0.54, and 0.57 on the low-grade Challenge data set for the complete, core, and enhancing regions.Conclusions: The experimental results show that the proposed algorithm is valid and ranks 2nd compared with the state-of-the-art tumor segmentation algorithms in the MICCAI BRATS 2013 challenge.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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