Does Body Mass Index Modify Memory, Reasoning, and Speed of Processing Training Effects in Older Adults.

Objective: To describe 10-year trajectories of cognitive performance by body mass index (BMI) class and to investigate BMI differences in response to memory, reasoning, and speed of processing training in older adults.Methods: This is a secondary analysis of the multisite, randomized trial Advanced...

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Publicado en:Obesity (19307381) Vol. 24; no. 11; pp. 2319 - 2327
Autores principales: Clark, Daniel O., Xu, Huiping, Callahan, Christopher M., Unverzagt, Frederick W.
Formato: research randomized controlled trial Journal Article
Publicado: Wiley-Blackwell Nov2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2016
      vid: 24
      iid: 11
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1002/oby.21631
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        atl: Does Body Mass Index Modify Memory, Reasoning, and Speed of Processing Training Effects in Older Adults.
      aug:
        au:
          Clark, Daniel O.
          Xu, Huiping
          Callahan, Christopher M.
          Unverzagt, Frederick W.
        affil: Indiana University Center for Aging Research, Indianapolis Indiana, USA
      sug:
        subj:
          Cognition
          Learning
          Memory
          Body Mass Index
          Female
          Aged, 80 and Over
          Human
          Male
          Obesity Physiopathology
          Aged
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Randomized Controlled Trials
          Aged, 80 & over
          Aged: 65+ years
          Female
          Male
      ab: Objective: To describe 10-year trajectories of cognitive performance by body mass index (BMI) class and to investigate BMI differences in response to memory, reasoning, and speed of processing training in older adults.Methods: This is a secondary analysis of the multisite, randomized trial Advanced Cognitive Training for Independent and Vital Elderly. There were 701 older adults with normal weight, 1,081 with overweight, and 902 with obesity (mean age 73.6) randomized to memory training, reasoning training, speed of processing training, or no-training control group. Participants completed memory, reasoning, and speed of processing tests. Baseline sociodemographic, health, and chronic disease measures were included as covariates in analyses.Results: The 10-year trajectories of memory, reasoning, or speed of processing performance did not differ by BMI status among the participants randomized to the untrained control arm. The training effect on the reasoning and speed of processing outcomes did not differ by BMI status. The training effect on the memory outcome in participants with a BMI indicating obesity, however, was just 38% of that observed in participants with normal-weight BMI.Conclusions: These analyses of data from the largest trial of cognitive training ever conducted suggest that older adults with obesity may be less responsive to memory training.
      pubtype: Academic Journal
      doctype:
        research
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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