The e-MSWS-12: improving the multiple sclerosis walking scale using item response theory.

Background: The Multiple Sclerosis Walking Scale (MSWS-12) is the predominant patient-reported measure of multiple sclerosis (MS) -elated walking ability, yet it had not been analyzed using item response theory (IRT), the emerging standard for patient-reported outcome (PRO) validation. This study ai...

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Publicado en:Quality of Life Research Vol. 25; no. 12; pp. 3221 - 3231
Autores principales: Engelhard, Matthew, Schmidt, Karen, Engel, Casey, Brenton, J. Nicholas, Patek, Stephen, Goldman, Myla, Engelhard, Matthew M, Schmidt, Karen M, Engel, Casey E, Patek, Stephen D, Goldman, Myla D
Formato: research Journal Article
Publicado: Springer Nature Dec2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2016
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      pub: Springer Nature
      place: New York, New York
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        atl: The e-MSWS-12: improving the multiple sclerosis walking scale using item response theory.
      aug:
        au:
          Engelhard, Matthew
          Schmidt, Karen
          Engel, Casey
          Brenton, J. Nicholas
          Patek, Stephen
          Goldman, Myla
          Engelhard, Matthew M
          Schmidt, Karen M
          Engel, Casey E
          Patek, Stephen D
          Goldman, Myla D
        affil: Department of Systems and Information Engineering , University of Virginia , Charlottesville 22904 USA
      sug:
        subj:
          Disability Evaluation
          Multiple Sclerosis Therapy
          Sickness Impact Profile
          Walking Physiology
          Middle Age
          Aged
          Male
          Aged, 80 and Over
          Female
          Adult
          Human
          Funding Source
          Scales
          Clinical Assessment Tools
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Adult: 19-44 years
          Male
          Female
      ab: Background: The Multiple Sclerosis Walking Scale (MSWS-12) is the predominant patient-reported measure of multiple sclerosis (MS) -elated walking ability, yet it had not been analyzed using item response theory (IRT), the emerging standard for patient-reported outcome (PRO) validation. This study aims to reduce MSWS-12 measurement error and facilitate computerized adaptive testing by creating an IRT model of the MSWS-12 and distributing it online.Methods: MSWS-12 responses from 284 subjects with MS were collected by mail and used to fit and compare several IRT models. Following model selection and assessment, subpopulations based on age and sex were tested for differential item functioning (DIF).Results: Model comparison favored a one-dimensional graded response model (GRM). This model met fit criteria and explained 87 % of response variance. The performance of each MSWS-12 item was characterized using category response curves (CRCs) and item information. IRT-based MSWS-12 scores correlated with traditional MSWS-12 scores (r = 0.99) and timed 25-foot walk (T25FW) speed (r =  -0.70). Item 2 showed DIF based on age (χ 2 = 19.02, df = 5, p < 0.01), and Item 11 showed DIF based on sex (χ 2 = 13.76, df = 5, p = 0.02).Conclusions: MSWS-12 measurement error depends on walking ability, but could be lowered by improving or replacing items with low information or DIF. The e-MSWS-12 includes IRT-based scoring, error checking, and an estimated T25FW derived from MSWS-12 responses. It is available at https://ms-irt.shinyapps.io/e-MSWS-12 .
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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