Identification of Novel Small Molecules That Bind to the Loop2 Region of Sclerostin - an in silico Computational Analysis.
The goal of this study was to identify small molecular weight compounds that bind to sclerostin using in silico methods because of the established importance of sclerostin-based therapies for the treatment of disease characterized by low bone mass. The zinc database (Zdb) revealed that nine potentia...
| Publicado en: | Physiological Research Vol. 65; no. 5; pp. 871 - 879 |
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| Autores principales: | , , , |
| Formato: | Journal Article |
| Publicado: |
Institute of Physiology, Academy of Sciences of the Czech Republic
2016
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| Acceso en línea: | Ver este registro en EBSCOhost |