Explicit memory performance in infants of diabetic mothers at 1 year of age.
The aim of the present research was to investigate the impact of abnormal fetal environment on explicit memory performance. Based on animal models, it was hypothesized that infants of diabetic mothers (IDMs) experience perturbations in memory performance due to exposure to multiple neurologic risk f...
| Publicado en: | Developmental Medicine & Child Neurology Vol. 47; no. 8; pp. 525 - 532 |
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| Autores principales: | , , , , |
| Formato: | research Journal Article |
| Publicado: |
Wiley-Blackwell
Aug2005
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=119425190&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 119425190 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00121622 1VN jtl: Developmental Medicine & Child Neurology issn: 00121622 maglogo: Y pubinfo: dt: Aug2005 vid: 47 iid: 8 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 119425190 119425190 NLM16108452 119425190 10.1017/S0012162205001039 NLM16108452 PMC2829746 119425190 ppf: 525 ppct: 7 formats: tig: atl: Explicit memory performance in infants of diabetic mothers at 1 year of age. aug: au: DeBoer, Tracy Wewerka, Sandi Bauer, Patricia J Georgieff, Michael K Nelson, Charles A affil: Institute of Child Development and Center for Neurobehavioral Development, University of Minnesota, USA sug: subj: Memory Disorders Epidemiology Mothers Statistics and Numerical Data Memory Disorders Diagnosis Diabetes Mellitus Epidemiology Female Cognition Disorders Diagnosis Videorecording Cognition Disorders Epidemiology Memory Adult Neuropsychological Tests Human Infant Severity of Illness Indices Gestational Age Behavior Validation Studies Comparative Studies Evaluation Research Multicenter Studies Impact of Events Scale Scales Adult: 19-44 years Infant: 1-23 months Female ab: The aim of the present research was to investigate the impact of abnormal fetal environment on explicit memory performance. Based on animal models, it was hypothesized that infants of diabetic mothers (IDMs) experience perturbations in memory performance due to exposure to multiple neurologic risk factors including: chronic hypoxia, hyperglycemia/reactive hypoglycemia, and iron deficiency. Memory performance, as measured by the elicited/deferred imitation paradigm, was compared between 13 IDMs (seven females, six males; mean age 365 days, SD 11) and 16 typically developing children (seven females, nine males; mean age 379 days, SD 9). The IDM group was characterized by shorter gestational age (mean 38w, SD 2), greater standardized birthweight scores (mean 3797g, SD 947), and lower iron stores (mean ferritin concentration 87C microg/L, SD 68) in comparison with the control group (mean gestational age: 40w, SD 1; mean birthweight: 3639g, SD 348; mean newborn ferritin concentration 140 microg/L, SD 46). After statistically controlling for both gestational age and global cognitive abilities, IDMs demonstrated a deficit in the ability to recall multi-step event sequences after a delay was imposed. These findings highlight the importance of the prenatal environment on subsequent mnemonic behavior and suggest a connection between metabolic abnormalities during the prenatal period, development of memory, circuitry, and behavioral mnemonic performance. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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