Does general movements quality in term infants predict cerebral palsy and milder forms of limited mobility at 6 years?

Aim: To evaluate in term infants associations between quality of general movements and developmental outcome in term infants at 6 years with either cerebral palsy (CP) or limited mobility without CP.Method: Participants of this prospective study were 145 term infants (86 male, 59 female). Their gene...

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Publicado en:Developmental Medicine & Child Neurology Vol. 58; no. 12; pp. 1310 - 1317
Autores principales: Iersel, Patricia A M, Bakker, Saskia C M, Jonker, Arnold J H, Hadders‐Algra, Mijna
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Dec2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2016
      vid: 58
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/dmcn.13228
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        atl: Does general movements quality in term infants predict cerebral palsy and milder forms of limited mobility at 6 years?
      aug:
        au:
          Iersel, Patricia A M
          Bakker, Saskia C M
          Jonker, Arnold J H
          Hadders‐Algra, Mijna
        affil: Department of Physical Therapy, Gelre Hospital, Apeldoorn the Netherlands
      sug:
        subj:
          Cerebral Palsy Diagnosis
          Motor Activity Physiology
          Infant Behavior
          Symptoms
          Severity of Illness Indices
          Female
          Child
          Prognosis
          Infant, Newborn
          Sensitivity and Specificity
          Prospective Studies
          Infant
          Male
          Clinical Assessment Tools
          Human
          Child: 6-12 years
          Infant, Newborn: birth-1 month
          Infant: 1-23 months
          Female
          Male
      ab: Aim: To evaluate in term infants associations between quality of general movements and developmental outcome in term infants at 6 years with either cerebral palsy (CP) or limited mobility without CP.Method: Participants of this prospective study were 145 term infants (86 male, 59 female). Their general movements quality was assessed at 'writhing' and 'fidgety' general movements age (3wks and 13wks post term). The assessment at 6 years consisted of a neurological examination, including assessment of minor neurological dysfunction (MND), evaluation of mobility with the Movement Assessment Battery for Children, and of behaviour and learning problems with questionnaires.Results: Definitely abnormal general movements at writhing age were not associated with CP, whereas definitely abnormal general movements at fidgety age were (sensitivity 60%; specificity 91%; positive predictive value 19%, negative predictive value 98%). In children without CP, general movements quality was not associated with limited mobility, but it was associated to a minor extent with MND.Interpretation: In term infants, definitely abnormal general movements at fidgety age do predict CP, but with lower accuracy than in preterm infants. General movements quality does not predict limited mobility in children without CP. The study supports suggestions that predictive value of general movements assessment in term infants is lower than that in preterm infants.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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