Clinical and Radiologic Follow-up Study for Biopsy Diagnosis of Radial Scar/Radial Sclerosing Lesion without Other Atypia.
To determine the incidence of malignancy for radial scars (RS)/radial sclerosing lesions (RSL) without associated atypia or malignancy identified at needle biopsy. Retrospective review of the pathology data base from January 2004 to July 2013 yielded 100 needle biopsies diagnosed as RS/RSL without a...
| Publicado en: | Breast Journal Vol. 22; no. 6; pp. 637 - 645 |
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| Autores principales: | , , , |
| Formato: | diagnostic images pictorial research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Nov/Dec2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=119458187&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 119458187 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 1075122X ET6 jtl: Breast Journal issn: 1075122X maglogo: Y pubinfo: dt: Nov/Dec2016 vid: 22 iid: 6 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 119458187 119458187 119458187 10.1111/tbj.12645 119458187 ppf: 637 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Clinical and Radiologic Follow-up Study for Biopsy Diagnosis of Radial Scar/Radial Sclerosing Lesion without Other Atypia. aug: au: Kalife, Elizabeth Tágide Lourenco, Ana P. Baird, Grayson L. Wang, Yihong affil: Department of Pathology, Alpert Medical School of Brown University, Rhode Island Hospital, Providence Rhode Island sug: subj: Biopsy Breast Neoplasms Diagnosis Diagnosis Methods Breast Neoplasms Classification Breast Pathology Retrospective Design Human Record Review Descriptive Statistics Data Analysis Software P-Value Kaplan-Meier Estimator T-Tests Confidence Intervals Odds Ratio Adult Middle Age Aged Aged, 80 and Over Calcinosis Breast Neoplasms Surgery Academic Medical Centers Rhode Island Rhode Island Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over ab: To determine the incidence of malignancy for radial scars (RS)/radial sclerosing lesions (RSL) without associated atypia or malignancy identified at needle biopsy. Retrospective review of the pathology data base from January 2004 to July 2013 yielded 100 needle biopsies diagnosed as RS/RSL without associated atypia/malignancy. The RS/RSL was considered 'incidental' if the target was calcifications and 'targeted' if imaging revealed a mass, architectural distortion, or suspicious magnetic resonance imaging enhancement. The electronic medical record was used to identify surgical pathology, follow-up imaging, and clinical course; all pathology slides and imaging were reviewed by a board-certified pathologist and radiologist, respectively. Patient age, laterality, RS/RSL size, microcalcifications, and associated benign lesions were recorded. Among 100 cases, 54 were 'incidental' and 46 were 'targeted.' In the incidental group, 14 underwent excision, 30 had imaging follow-up, and 10 were lost to follow-up. In the targeted group, 27 underwent excision, 11 had imaging follow-up, and 8 were lost to follow-up. Atypia was identified in four excisions: three from the incidental group and one from the targeted group. Among these, three had negative imaging follow-up (mean 45 months; range 15-60 months); the fourth patient (one of the incidental group) underwent excision alone. One of the 27 'targeted' patients who underwent excision developed ductal carcinoma in situ of the contralateral breast at 96 months. There have been no ipsilateral malignancies. We found no evidence of associated malignancy at excision for either incidental or targeted biopsies of RS/RSL without atypia. Our study suggests that close imaging follow-up is adequate for patients with RS/RSL without associated atypia/malignancy on needle biopsy. pubtype: Academic Journal doctype: diagnostic images pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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