Targeting 24 bp within Telomere Repeat Sequences with Tandem Tetramer Pyrrole-Imidazole Polyamide Probes.

Synthetic molecules that bind sequence-specifically to DNA have been developed for varied biological applications, including anticancer activity, regulation of gene expression, and visualization of specific genomic regions. Increasing the number of base pairs targeted by synthetic molecules strength...

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Publicado en:	Journal of the American Chemical Society Vol. 138; no. 42; pp. 14100 - 14108
Autores principales:	Yusuke Kawamoto, Chandran, Anandhakumar, Hashiya, Kaori, Toshikazu Bando, Sugiyama, Hiroshi, Asuka Sasaki, Satoru Ide, Kazuhiro Maeshima
Formato:	Artículo
Publicado:	American Chemical Society 10/26/2016
Materias:	Effect of chemicals on DNA DNA Telomeres Biotin metabolism Dimerization Therapeutics
Acceso en línea:	Ver este registro en EBSCOhost