Target attainment analysis and optimal sampling designs for population pharmacokinetic study on piperacillin/tazobactam in neonates and young infants.

Objectives: Population pharmacokinetic (popPK) analyses for piperacillin/tazobactam in neonates and infants of less than 2 months of age have been performed by our group previously. The results indicate that a dose of 44.44/5.56 mg/kg piperacillin/tazobactam every 8 or 12 h may not be enough for con...

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Publicado en:European Journal of Clinical Pharmacology Vol. 72; no. 12; pp. 1479 - 1489
Autores principales: Chen, Yewei, Lu, Jinmiao, Dong, Min, Wu, Dan, Zhu, Yiqing, Li, Qin, Chen, Chao, Li, Zhiping
Formato: equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Dec2016
Acceso en línea:Ver este registro en EBSCOhost