MDM2 gene amplification and transcript levels in human sarcomas: relationship to TP53 gene status.
Background: Alterations of the TP53 tumor suppressor gene appear to be implicated in the tumorigenesis and progression of several types of human cancer, including different histologic subtypes of sarcomas. The MDM2 (murine double minute-2) gene encodes a nuclear phosphoprotein that may interact with...
| Publicado en: | JNCI: Journal of the National Cancer Institute Vol. 86; no. 17; pp. 1297 - 1303 |
|---|---|
| Autores principales: | , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Oxford University Press / USA
9/7/94
|
| Acceso en línea: | Ver este registro en EBSCOhost |