Altered brain network topology in left-behind children: A resting-state functional magnetic resonance imaging study.

Whether a lack of direct parental care affects brain function in children is an important question, particularly in developing countries where hundreds of millions of children are left behind when their parents migrate for economic or political reasons. In this study, we investigated changes in the...

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Publicado en:Child Abuse & Neglect Vol. 62; pp. 89 - 100
Autores principales: Zhao, Youjin, Du, Meimei, Gao, Xin, Xiao, Yuan, Shah, Chandan, Sun, Huaiqiang, Chen, Fuqin, Yang, Lili, Yan, Zhihan, Fu, Yuchuan, Lui, Su
Formato: Artículo
Publicado: Elsevier B.V. Dec2016
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2016
      vid: 62
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      pub: Elsevier B.V.
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        119778809
        10.1016/j.chiabu.2016.10.013
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        atl: Altered brain network topology in left-behind children: A resting-state functional magnetic resonance imaging study.
      aug:
        au:
          Zhao, Youjin
          Du, Meimei
          Gao, Xin
          Xiao, Yuan
          Shah, Chandan
          Sun, Huaiqiang
          Chen, Fuqin
          Yang, Lili
          Yan, Zhihan
          Fu, Yuchuan
          Lui, Su
        affil:
          Department of Radiology, the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Zhejiang 325035, PR China
          Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, Chengdu 610041, PR China
      su:
        Child psychology
        Topology
        Brain function localization
        Statistical correlation
        Developing countries
      sug:
        subj:
          Child psychology
          Topology
          Brain function localization
          Statistical correlation
          Developing countries
      keyword:
        Brain network
        Graph analysis
        Left-behind children (LBC)
        Resting-state functional magnetic resonance imaging (r-fMRI)
        Brain network
        Graph analysis
        Left-behind children (LBC)
        Resting-state functional magnetic resonance imaging (r-fMRI)
      ab: Whether a lack of direct parental care affects brain function in children is an important question, particularly in developing countries where hundreds of millions of children are left behind when their parents migrate for economic or political reasons. In this study, we investigated changes in the topological architectures of brain functional networks in left-behind children (LBC). Resting-state functional magnetic resonance imaging data were obtained from 26 LBC and 21 children living within their nuclear family (non-LBC). LBC showed a significant increase in the normalized characteristic path length (λ), suggesting a decrease in efficiency in information access, and altered nodal centralities in the fronto-limbic regions and motor and sensory systems. Moreover, a decreased nodal degree and the nodal betweenness of the right rectus gyrus were positively correlated with annual family income. The present study provides the first empirical evidence that suggests that a lack of direct parental care could affect brain functional development in children, particularly involving emotional networks.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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