Vasculitis in the autoinflammatory diseases.
Purpose Of Review: This article addresses the prevalence and relationship between autoinflammatory diseases and vasculitis.Recent Findings: Autoimmune diseases (AIDs) are a group of syndromes characterized by episodes of unprovoked inflammation due to dysregulation of the innate immune system. Despi...
| Publicado en: | Current Opinion in Rheumatology Vol. 29; no. 1; pp. 4 - 12 |
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| Autores principales: | , |
| Formato: | review Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
Jan2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=120045518&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 120045518 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10408711 IR0 jtl: Current Opinion in Rheumatology issn: 10408711 maglogo: N pubinfo: dt: Jan2017 vid: 29 iid: 1 pid: 433 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 120045518 120045518 NLM27755121 120045518 10.1097/BOR.0000000000000347 NLM27755121 120045518 ppf: 4 ppct: 8 formats: tig: atl: Vasculitis in the autoinflammatory diseases. aug: au: Peleg, Hagit Ben-Chetrit, Eldad affil: Rheumatology Unit, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. sug: subj: Hereditary Autoinflammatory Diseases Complications Vasculitis Etiology Uveitis Complications Synovitis Complications Autoimmune Diseases Complications Arthritis Complications Purpura, Schoenlein-Henoch Complications Skin Diseases Etiology Vasculitis Immunology Interleukin 1 Immunology Pyoderma Gangrenosum Complications Proteins ab: Purpose Of Review: This article addresses the prevalence and relationship between autoinflammatory diseases and vasculitis.Recent Findings: Autoimmune diseases (AIDs) are a group of syndromes characterized by episodes of unprovoked inflammation due to dysregulation of the innate immune system. Despite the common occurrence of rashes and other skin lesions in these diseases, vasculitis is reported in only a few. On the other hand, neutrophilic dermatoses are more prevalent. Large vessel vasculitis is reported in patients with Behcet's and Blau's syndromes. Small and medium size vasculitides are reported in familial Mediterranean fever mainly as Henoch-Schonlein purpura and polyarteritis nodosa, respectively. It is rarely described in hyper IgD with periodic fever syndrome, cryopyrin associated periodic syndromes, TNF receptor-associated periodic syndrome, deficiency of interleukin-1 receptor antagonist and pyoderma gangrenosum and acne syndrome. In most AID where bones and skin are mainly involved (CRMO, Majeed syndrome, Cherubism and DITRA) - vasculitis has not been described at all. In AID small vessel vasculitis affects mainly the skin with no involvement of internal organs.Summary: In AID, neutrophilic dermatoses are more common and prominent than vasculitis. This may reflect a minor role for interleukin-1 in the pathogenesis of vasculitis. The rarity of vasculitis in AID suggests that in most reported cases its occurrence has been probably coincidental rather than being an integral feature of the disease. pubtype: Academic Journal doctype: review Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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