Pyoderma gangrenosum: A clinico-epidemiological study.
Background: Pyoderma gangrenosum is a neutrophilic dermatosis of unknown etiology, with inconstant systemic associations and a variable prognosis.Aims: To study the clinical features and systemic associations of pyoderma gangrenosum and its response to treatment.Methods: All patients diagnosed to ha...
| Publicado en: | Indian Journal of Dermatology, Venereology & Leprology Vol. 83; no. 1; pp. 33 - 40 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Scientific Scholar LLC
Jan/Feb2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=120072937&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 120072937 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03786323 SV4 jtl: Indian Journal of Dermatology, Venereology & Leprology issn: 03786323 maglogo: N pubinfo: dt: Jan/Feb2017 vid: 83 iid: 1 pid: 56013 pub: Scientific Scholar LLC place: Pittsford, New York artinfo: ui: 120072937 120072937 NLM27549869 10.4103/0378-6323.188654 NLM27549869 120072937 ppf: 33 ppct: 7 formats: tig: atl: Pyoderma gangrenosum: A clinico-epidemiological study. aug: au: Riyaz, Najeeba Mary, Vineetha Sasidharanpillai, Sarita Roshin, Riyaz A Snigdha, Ottakandathil Latheef, Ettappurath N Abdul Rahima, Saleem Bindu, Valiaveetil Anupama, Ravindran N Sureshan, Deepthi N Sherjeena, Pentam Veil Beegum affil: Department of Dermatology, Government Medical College, Kozhikode, Kerala, India sug: subj: Immunoglobulins, Intravenous Administration and Dosage Pyoderma Gangrenosum Therapy Skin Transplantation Methods Pyoderma Gangrenosum Epidemiology Prospective Studies Male Sex Factors Child, Preschool Infant Adult Child Adolescence Female Middle Age Young Adult Pyoderma Gangrenosum Diagnosis Aged Arthritis Impact Measurement Scales Scales Child, Preschool: 2-5 years Infant: 1-23 months Adult: 19-44 years Child: 6-12 years Adolescent: 13-18 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Background: Pyoderma gangrenosum is a neutrophilic dermatosis of unknown etiology, with inconstant systemic associations and a variable prognosis.Aims: To study the clinical features and systemic associations of pyoderma gangrenosum and its response to treatment.Methods: All patients diagnosed to have pyoderma gangrenosum at the dermatology department of the Government Medical College, Kozhikode, from January 01, 2005 to December 31, 2014 were included in this prospective study.Results: During the 10-year study period, 61 patients were diagnosed to have pyoderma gangrenosum. A male predilection was noted. The most common clinical type was ulcerative pyoderma gangrenosum (90.2%). More than 60% of patients had lesions confined to the legs; 78.7% had a single lesion and 27.9% had systemic associations. Most patients required systemic steroids. Patients with disease resistant to steroid therapy were treated with intravenous immunoglobulin G and split-thickness skin grafts under immunosuppression induced by dexamethasone pulse therapy. All except one patient attained complete disease resolution.Limitations: The main limitation of our study was the small sample size.Conclusions: The male predilection documented by us was contrary to most previous studies. We found split-thickness skin graft to be a useful option in resistant cases. More prospective studies may enable the formulation of better diagnostic criteria for pyoderma gangrenosum and improve its management. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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