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Sepsis in Patients With Cirrhosis.

Patients with cirrhosis are at high risk for sepsis and sepsis-related mortality. Aggressive treatment aimed at avoidance of hypo-perfusion and prompt identification and treatment of the causative organism can improve patients' survival. Fluid administration is the first-line treatment to improve pe...

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Published in:AACN Advanced Critical Care Vol. 27; no. 4; pp. 408 - 420
Main Authors: McLaughlin, Diane, Shellenback, Lori
Format: pictorial tables/charts Journal Article
Published: American Association of Critical-Care Nurses Oct-Dec2016
Online Access:View this record in EBSCOhost
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    pubinfo:
      dt: Oct-Dec2016
      vid: 27
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      pid: 2559
      pub: American Association of Critical-Care Nurses
      place: Alisa Veijo, California
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        10.4037/aacnacc2016716
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      tig:
        atl: Sepsis in Patients With Cirrhosis.
      aug:
        au:
          McLaughlin, Diane
          Shellenback, Lori
        affil: Acute Care Nurse Practitioner, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL 32224
      sug:
        subj:
          Liver Cirrhosis Complications
          Systemic Inflammatory Response Syndrome Therapy
          Systemic Inflammatory Response Syndrome Diagnosis
          Systemic Inflammatory Response Syndrome Complications
          Systemic Inflammatory Response Syndrome Symptoms
          Hematologic Tests
          Fluid Therapy
          Goals and Objectives
          Ultrasonography Utilization
          Antibiotics Administration and Dosage
          Vasoconstrictor Agents Administration and Dosage
          Respiratory System Physiopathology
          Kidney Failure, Acute
          Hepatorenal Syndrome
          Glycemic Control
          Adrenal Insufficiency
          Malnutrition
      ab: Patients with cirrhosis are at high risk for sepsis and sepsis-related mortality. Aggressive treatment aimed at avoidance of hypo-perfusion and prompt identification and treatment of the causative organism can improve patients' survival. Fluid administration is the first-line treatment to improve perfusion to vital organs; however, care should be taken to assess true intravascular volume status. In patients with adequate intravascular volume, vasopressors are then added to support blood pressure. Complications of cirrhosis often worsen in the setting of sepsis. Portosystemic encephalopathy, pulmonary complications, renal complications, adrenal insufficiency, malnutrition, and insufficient glucose control all must be considered and treated to support a patient with cirrhosis through sepsis. The quality of care that these patients receive ultimately influences their survival.
      pubtype: Academic Journal
      doctype:
        pictorial
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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