A Naphthalenic Derivative ND-1 Inhibits Thrombus Formation by Interfering the Binding of Fibrinogen to Integrin αIIbβ3.

Integrin αIIbβ3 plays a crucial role in the process of platelet aggregation. Three integrin αIIbβ3 antagonists (abciximab, eptifibatide, and tirofiban) have been approved by FDA for clinical use. Unfortunately, they all showed severe side effects such as thrombocytopenia and bleeding risk. Thus, res...

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Publicado en:	BioMed Research International Vol. 2016; pp. 1 - 9
Autores principales:	Ding, Xue, Liu, Tong-dan, Xie, Zhou-ling, Zhao, Qi, Cao, Yuan, Liu, Xiao-dong, Wang, Cai-hui, Gamariel, Rwibasira Rudinga, Ming, Xin, Li, Zhi-yu, Kong, Yi
Formato:	pictorial research tables/charts Journal Article
Publicado:	Wiley-Blackwell 12/20/2016
Acceso en línea:	Ver este registro en EBSCOhost