Do quantitative and qualitative shear wave elastography have a role in evaluating musculoskeletal soft tissue masses?
Objectives: To determine if quantitative and qualitative shear wave elastography have roles in evaluating musculoskeletal masses.Methods: 105 consecutive patients, prospectively referred for biopsy within a specialist sarcoma centre, underwent B-mode, quantitative (m/s) and qualitative (colour map)...
| Published in: | European Radiology Vol. 27; no. 2; pp. 723 - 732 |
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| Main Authors: | , , , , , , |
| Format: | Journal Article |
| Published: |
Springer Nature
Feb2017
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=120531408&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 120531408 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Feb2017 vid: 27 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 120531408 120531408 NLM27277260 10.1007/s00330-016-4427-y NLM27277260 120531408 ppf: 723 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Do quantitative and qualitative shear wave elastography have a role in evaluating musculoskeletal soft tissue masses? aug: au: Pass, B. Jafari, M. Rowbotham, E. Hensor, E. Gupta, H. Robinson, P. Hensor, E M A affil: Musculoskeletal Centre X-Ray Department, Leeds Teaching Hospitals Trust , Chapel Allerton Hospital , Leeds UK sug: subj: Ultrasonography, Doppler, Color Methods Ultrasonography Methods Soft Tissue Neoplasms Sarcoma Male Middle Age Chemistry, Physical Sensitivity and Specificity Adult Aged Liposarcoma Biopsy Female Neoplasms, Vascular Tissue Reproducibility of Results Young Adult Ultrasonography Aged, 80 and Over Middle Aged: 45-64 years Adult: 19-44 years Aged: 65+ years Aged, 80 & over Male Female ab: Objectives: To determine if quantitative and qualitative shear wave elastography have roles in evaluating musculoskeletal masses.Methods: 105 consecutive patients, prospectively referred for biopsy within a specialist sarcoma centre, underwent B-mode, quantitative (m/s) and qualitative (colour map) shear wave elastography. Reference was histology from subsequent biopsy or excision where possible. Statistical modelling was performed to test elastography data and/or B-mode imaging in predicting malignancy.Results: Of 105 masses, 39 were malignant and 6 had no histology but benign characteristics at 12 months. Radiologist agreement for B-mode and elastography was moderate to excellent Kw 0.52-0.64; PABAKw 0.85-0.90). B-Mode imaging had 78.8% specificity, 76.9% sensitivity for malignancy. Quantitatively, adjusting for age, B-mode and lesion volume there was no statistically significant association between longitudinal velocity and malignancy (OR [95% CI] 0.40[0.10, 1.60], p=0.193), but some evidence that higher transverse velocity was associated with decreased odds of malignancy (0.28[0.06, 1.28], p=0.101). Qualitatively malignant masses tended to be towards the blue spectrum (lower velocities); 39.5% (17/43) of predominantly blue masses were malignant, compared to 14.3% (1/7) of red lesions.Conclusions: Quantitatively and qualitatively there is no statistically significant association between shear wave velocity and malignancy. There is no clear additional role to B-mode imaging currently.Key Points: • Correlation between shear wave velocity and soft tissue malignancy was statistically insignificant • B-mode ultrasound is 76.9 % sensitive and 78.8 % specific • Statistical models show elastography does not significantly add to lesion assessment. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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