Metastatic Crohn’s Disease: An Approach to an Uncommon but Important Cutaneous Disorder.
Objective. To provide physicians with a clinical approach to metastatic Crohn’s disease (MCD). Main Message. Metastatic Crohn’s disease, defined as skin lesions present in areas noncontiguous with the gastrointestinal tract, is the rarest cutaneous manifestation of Crohn’s disease. MCD lesions vary...
| Publicado en: | BioMed Research International Vol. 2017; pp. 1 - 7 |
|---|---|
| Autores principales: | , , |
| Formato: | pictorial review tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
1/3/2017
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=120537020&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 120537020 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 1/3/2017 vid: 2017 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 120537020 120537020 120537020 10.1155/2017/8192150 120537020 ppf: 1 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Metastatic Crohn’s Disease: An Approach to an Uncommon but Important Cutaneous Disorder. aug: au: Aberumand, Babak Howard, Jessica Howard, John affil: Schulich School of Medicine & Dentistry, Western University, London, ON, Canada sug: subj: Skin Diseases Etiology Crohn Disease Physiopathology Crohn Disease Symptoms Male Gastrointestinal Diseases Inflammation Female Adult Adult: 19-44 years Male Female ab: Objective. To provide physicians with a clinical approach to metastatic Crohn’s disease (MCD). Main Message. Metastatic Crohn’s disease, defined as skin lesions present in areas noncontiguous with the gastrointestinal tract, is the rarest cutaneous manifestation of Crohn’s disease. MCD lesions vary in morphology and can arise anywhere on the skin. MCD presents equally in both sexes and across age groups. Cutaneous findings may precede, develop concurrently with, or follow gastrointestinal involvement. A detailed history and thorough physical examination including a full-skin exam may help to exclude other dermatoses, as MCD can mimic other common disorders. A biopsy is required for a definitive diagnosis. Treatment options for MCD remain underwhelming due to the lack of randomized control studies and varying responses of reported therapeutic methods. Topical, intralesional, and systemic corticosteroids, antibiotics, traditional immunosuppressants, and surgery have shown mixed results. Recently, biologics have shown promise, even with refractory cases of MCD. Conclusion. MCD is an important cutaneous manifestation of this inflammatory disorder. Although a rare entity, early recognition can provide opportunity for successful therapeutic intervention. pubtype: Academic Journal doctype: pictorial review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|