High-Flow Nasal Cannula in Critically Ill Subjects With or at Risk for Respiratory Failure: A Systematic Review and Meta-Analysis.
High-flow nasal cannula (HFNC) oxygen delivery has been gaining attention as an alternative means of respiratory support for critically ill patients, with recent studies suggesting equivalent outcomes when compared with other forms of oxygen therapy delivery. The main objective of this review was to...
| Publicado en: | Respiratory Care Vol. 62; no. 1; pp. 123 - 133 |
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| Autores principales: | , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
Jan2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=120544365&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 120544365 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00201324 4GG jtl: Respiratory Care issn: 00201324 maglogo: N pubinfo: dt: Jan2017 vid: 62 iid: 1 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 120544365 120544365 120544365 10.4187/respcare.04831 120544365 ppf: 123 ppct: 10 formats: fmt: @attributes: type: P tig: atl: High-Flow Nasal Cannula in Critically Ill Subjects With or at Risk for Respiratory Failure: A Systematic Review and Meta-Analysis. aug: au: Nedel, Wagner Luis Deutschendorf, Caroline Rodrigues Filho, Edison Moraes affil: ICU, Hospital Nossa Senhora da Conceição and the ICU, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil sug: subj: Nasal Cannula Critically Ill Patients Respiratory Failure Risk Factors Oxygen Therapy Methods Human Systematic Review Meta Analysis Descriptive Statistics Confidence Intervals Odds Ratio Respiratory Failure Prevention and Control Noninvasive Procedures Respiration, Artificial Oxygenation Carbon Dioxide Comparative Studies Mortality Medline Cochrane Library Embase Data Analysis Software Mantel-Haenszel Test Chi Square Test Scales Male Female Adult Middle Age Aged P-Value Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: High-flow nasal cannula (HFNC) oxygen delivery has been gaining attention as an alternative means of respiratory support for critically ill patients, with recent studies suggesting equivalent outcomes when compared with other forms of oxygen therapy delivery. The main objective of this review was to extract current data about the efficacy of HFNC in critically ill subjects with or at risk for respiratory failure. We performed a systematic review of publications (from database inception to October 2015) that evaluated HFNC in critically ill subjects with or at risk for acute respiratory failure and performed a meta-analysis comparing HFNC with noninvasive ventilation (NIV) and with standard oxygen therapy regarding major outcomes: incidence of invasive mechanical ventilation and ICU mortality. A total of 9 studies were included. HFNC was not associated with a reduction in the incidence of invasive mechanical ventilation compared with NIV (odds ratio [OR] 0.83,95% Cl 0.57-1.20, P = .31) or standard oxygen therapy (OR 0.49, 95% Cl 0.22-1.08, P = .17). Additionally, HFNC use did not reduce ICU mortality compared with NIV (OR 0.72, 95% Cl 0.23-2.21, P = .56) or with standard oxygen therapy (OR 0.69, 95% Cl 0.33-1.42, P = .29). There was a trend toward better oxygenation compared with conventional oxygen therapy but a worse gas exchange compared with NIV. At this moment, HFNC therapy seems not to be superior to conventional oxygen therapy or NIV in terms of invasive mechanical ventilation rate or ICU mortality in critical illness, but new studies are needed to determine whether HFNC is associated with any difference in major outcomes when compared with other techniques. pubtype: Academic Journal doctype: meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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