Early Diagnosis of Helicobacter pylori Infection in Vietnamese Patients with Acute Peptic Ulcer Bleeding: A Prospective Study.

Aims. To investigate H. pylori infection rate and evaluate a combined set of tests for H. pylori diagnosis in Vietnamese patients with acute peptic ulcer bleeding (PUD). Methods. Consecutive patients with acute PUB were enrolled prospectively. Rapid urease test (RUT) with 3 biopsies was carried out...

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Publicado en:Gastroenterology Research & Practice pp. 1 - 8
Autores principales: Quach, Duc Trong, Luu, Mai Ngoc, Hiyama, Toru, To, Thuy-HuongThi, Bui, Quy Nhuan, Tran, Tuan Anh, Tran, Binh Duy, Vo, Minh-Cong Hong, Tanaka, Shinji, Uemura, Naomi
Formato: Journal Article
Publicado: Wiley-Blackwell 1/4/2017
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: Gastroenterology Research & Practice
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      dt: 1/4/2017
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        120551059
        10.1155/2017/3845067
        120551059
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        atl: Early Diagnosis of Helicobacter pylori Infection in Vietnamese Patients with Acute Peptic Ulcer Bleeding: A Prospective Study.
      aug:
        au:
          Quach, Duc Trong
          Luu, Mai Ngoc
          Hiyama, Toru
          To, Thuy-HuongThi
          Bui, Quy Nhuan
          Tran, Tuan Anh
          Tran, Binh Duy
          Vo, Minh-Cong Hong
          Tanaka, Shinji
          Uemura, Naomi
        affil: Department of Internal Medicine, University of Medicine and Pharmacy, Ho Chi Minh, Vietnam
      sug:
      ab: Aims. To investigate H. pylori infection rate and evaluate a combined set of tests for H. pylori diagnosis in Vietnamese patients with acute peptic ulcer bleeding (PUD). Methods. Consecutive patients with acute PUB were enrolled prospectively. Rapid urease test (RUT) with 3 biopsies was carried out randomly. Patients without RUT or with negative RUT received urea breath test (UBT) and serological and urinary H. pylori antibody tests. H. pylori was considered positive if RUT or any noninvasive test was positive. Patients were divided into group A (RUT plus noninvasive tests) and group B (only noninvasive tests). Results. The overall H. pylori infection rate was 94.2% (161/171). Groups A and B had no differences in demographic characteristics, bleeding severity, endoscopic findings, and proton pump inhibitor use. H. pylori-positive rate in group A was significantly higher than that in group B (98.2% versus 86.7%, p=0.004). The positive rate of RUT was similar at each biopsy site but significantly increased if RUT results from 2 or 3 sites were combined (p<0.05). Conclusions. H. pylori infection rate in Vietnamese patients with acute PUB is high. RUT is an excellent test if at least 2 biopsies are taken.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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