Contrast-enhanced US-guided percutaneous biopsy of anterior mediastinal lesions.

Purpose: We aimed to explore the value of contrast-enhanced ultrasonography (CEUS) in guidance of percutaneous biopsy of anterior mediastinal lesions.Methods: Ninety patients with solitary anterior mediastinal lesions (55 males, 35 females; mean age, 46±4 years) were included. Patients were randomly...

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Publicado en:Diagnostic & Interventional Radiology Vol. 23; no. 1; pp. 43 - 49
Autores principales: Dong Yi, Mao Feng, Wang Wen-Ping, Ji Zheng-Biao, Pei-li Fan, Yi, Dong, Feng, Mao, Wen Ping, Wang, Zheng Biao, Ji, Fan, Pei Li
Formato: research randomized controlled trial Journal Article
Publicado: Galenos Yayinevi Tic. LTD. STI Jan/Feb2017
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Galenos Yayinevi Tic. LTD. STI
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        atl: Contrast-enhanced US-guided percutaneous biopsy of anterior mediastinal lesions.
      aug:
        au:
          Dong Yi
          Mao Feng
          Wang Wen-Ping
          Ji Zheng-Biao
          Pei-li Fan
          Yi, Dong
          Feng, Mao
          Wen Ping, Wang
          Zheng Biao, Ji
          Fan, Pei Li
        affil: Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, China.
      sug:
        subj:
          Mediastinal Neoplasms
          Mediastinal Neoplasms Pathology
          Image Enhancement Methods
          Male
          Female
          Ultrasonography
          Middle Age
          Adult
          Biopsy, Needle
          Human
          Contrast Media
          Aged
          Young Adult
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Randomized Controlled Trials
          Middle Aged: 45-64 years
          Adult: 19-44 years
          Aged: 65+ years
          Male
          Female
      ab: Purpose: We aimed to explore the value of contrast-enhanced ultrasonography (CEUS) in guidance of percutaneous biopsy of anterior mediastinal lesions.Methods: Ninety patients with solitary anterior mediastinal lesions (55 males, 35 females; mean age, 46±4 years) were included. Patients were randomly divided into CEUS group (n=45) and conventional ultrasonography (US) group (n=45). Real-time US-guided core needle (16 G) percutaneous biopsies were performed in all lesions. The display of internal mammary arteries, internal necrosis, and active areas were recorded and compared. Biopsy success rate and diagnostic accuracy were compared between the two groups.Results: Display rate of unenhanced internal necrosis was higher in the CEUS group than in the US group (88.9% vs. 46.7%, P = 0.041). With real-time CEUS guidance, internal mammary arteries were effectively displayed and avoided during biopsies in 68.9% of the lesions (31/45). Of the lesions, 88.9% (80/90) were histologically proven, including 13 benign lesions and 67 malignancies. There was a significant difference in the rate of successful puncture attempts between the two groups (P = 0.041). CEUS group had a higher biopsy success rate (100% vs. 95.5%, P = 0.045) and higher diagnostic accuracy (97.8% vs. 82.2%, P = 0.035) compared with the US group (P = 0.035).Conclusion: CEUS guidance is a promising technique in depicting internal necrotic areas, viable areas, and internal mammary arteries during percutaneous biopsy of anterior mediastinal lesion, with satisfying safety, accuracy, and success rates.
      pubtype: Academic Journal
      doctype:
        research
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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