Three-dimensional segmentation of retroperitoneal masses using continuous convex relaxation and accumulated gradient distance for radiotherapy planning.

An innovative algorithm has been developed for the segmentation of retroperitoneal tumors in 3D radiological images. This algorithm makes it possible for radiation oncologists and surgeons semiautomatically to select tumors for possible future radiation treatment and surgery. It is based on continuo...

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Publicado en:Medical & Biological Engineering & Computing Vol. 55; no. 1; pp. 1 - 16
Autores principales: Suárez-Mejías, Cristina, Pérez-Carrasco, Jose, Serrano, Carmen, López-Guerra, Jose, Parra-Calderón, Carlos, Gómez-Cía, Tomás, Acha, Begoña, Pérez-Carrasco, Jose Antonio, López-Guerra, Jose Luis
Formato: Journal Article
Publicado: Springer Nature Jan2017
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Three-dimensional segmentation of retroperitoneal masses using continuous convex relaxation and accumulated gradient distance for radiotherapy planning.
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          Suárez-Mejías, Cristina
          Pérez-Carrasco, Jose
          Serrano, Carmen
          López-Guerra, Jose
          Parra-Calderón, Carlos
          Gómez-Cía, Tomás
          Acha, Begoña
          Suárez-Mejías, Cristina
          Pérez-Carrasco, Jose Antonio
          López-Guerra, Jose Luis
          Parra-Calderón, Carlos
          Gómez-Cía, Tomás
          Acha, Begoña
        affil: Signal Theory and Communications Department , University of Seville , Seville Spain
      sug:
        subj:
          Retroperitoneal Neoplasms
          Radiotherapy, Computer-Assisted
          Retroperitoneal Neoplasms Radiotherapy
          Imaging, Three-Dimensional
          Algorithms
          Adolescence
          Observer Bias
          Young Adult
          Female
          Linear Regression
          Adult
          Male
          Adolescent: 13-18 years
          Adult: 19-44 years
          Female
          Male
      ab: An innovative algorithm has been developed for the segmentation of retroperitoneal tumors in 3D radiological images. This algorithm makes it possible for radiation oncologists and surgeons semiautomatically to select tumors for possible future radiation treatment and surgery. It is based on continuous convex relaxation methodology, the main novelty being the introduction of accumulated gradient distance, with intensity and gradient information being incorporated into the segmentation process. The algorithm was used to segment 26 CT image volumes. The results were compared with manual contouring of the same tumors. The proposed algorithm achieved 90 % sensitivity, 100 % specificity and 84 % positive predictive value, obtaining a mean distance to the closest point of 3.20 pixels. The algorithm's dependence on the initial manual contour was also analyzed, with results showing that the algorithm substantially reduced the variability of the manual segmentation carried out by different specialists. The algorithm was also compared with four benchmark algorithms (thresholding, edge-based level-set, region-based level-set and continuous max-flow with two labels). To the best of our knowledge, this is the first time the segmentation of retroperitoneal tumors for radiotherapy planning has been addressed.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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