A computerized volumetric segmentation method applicable to multi-centre MRI data to support computer-aided breast tissue analysis, density assessment and lesion localization.

Density assessment and lesion localization in breast MRI require accurate segmentation of breast tissues. A fast, computerized algorithm for volumetric breast segmentation, suitable for multi-centre data, has been developed, employing 3D bias-corrected fuzzy c-means clustering and morphological oper...

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Publicado en:Medical & Biological Engineering & Computing Vol. 55; no. 1; pp. 57 - 69
Autores principales: Ertas, Gokhan, Doran, Simon, Leach, Martin, Doran, Simon J, Leach, Martin O
Formato: algorithm diagnostic images equations & formulas pictorial research tables/charts Journal Article
Publicado: Springer Nature Jan2017
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: A computerized volumetric segmentation method applicable to multi-centre MRI data to support computer-aided breast tissue analysis, density assessment and lesion localization.
      aug:
        au:
          Ertas, Gokhan
          Doran, Simon
          Leach, Martin
          Doran, Simon J
          Leach, Martin O
        affil: Cancer Research UK Cancer Imaging Centre, Division of Radiotherapy and Imaging , The Institute of Cancer Research , 123 Old Brompton Road London SW7 3RP UK
      sug:
        subj:
          Magnetic Resonance Imaging Methods
          Image Processing, Computer Assisted
          Breast Neoplasms
          Breast Pathology
          Breast Neoplasms Diagnosis
          Female
          Algorithms
          Human
          Female
      ab: Density assessment and lesion localization in breast MRI require accurate segmentation of breast tissues. A fast, computerized algorithm for volumetric breast segmentation, suitable for multi-centre data, has been developed, employing 3D bias-corrected fuzzy c-means clustering and morphological operations. The full breast extent is determined on T1-weighted images without prior information concerning breast anatomy. Left and right breasts are identified separately using automatic detection of the midsternum. Statistical analysis of breast volumes from eighty-two women scanned in a UK multi-centre study of MRI screening shows that the segmentation algorithm performs well when compared with manually corrected segmentation, with high relative overlap (RO), high true-positive volume fraction (TPVF) and low false-positive volume fraction (FPVF), and has an overall performance of RO 0.94 ± 0.05, TPVF 0.97 ± 0.03 and FPVF 0.04 ± 0.06, respectively (training: 0.93 ± 0.05, 0.97 ± 0.03 and 0.04 ± 0.06; test: 0.94 ± 0.05, 0.98 ± 0.02 and 0.05 ± 0.07).
      pubtype: Academic Journal
      doctype:
        algorithm
        diagnostic images
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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