Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum.
Sixty-three amide alkaloids, including three new, piperflaviflorine A (1), piperflaviflorine B (2), and sarmentamide D (4), and two previously synthesized ones, (1 E,3S)-1-cinnamoyl-3-hydroxypyrrolidine (3) and N-[7'-(4'-methoxyphenyl)ethyl]-2-methoxybenzamide (5), were isolated from the aerial part...
| Publicado en: | Planta Medica Vol. 83; no. 1/2; pp. 143 - 151 |
|---|---|
| Autores principales: | , , , , , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Georg Thieme Verlag Stuttgart
2017
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=120819908&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 120819908 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00320943 NH9 jtl: Planta Medica issn: 00320943 maglogo: N pubinfo: dt: 2017 vid: 83 iid: 1/2 pid: 4536 pub: Georg Thieme Verlag Stuttgart artinfo: ui: 120819908 120819908 120819908 10.1055/s-0042-109778 120819908 ppf: 143 ppct: 8 formats: tig: atl: Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum. aug: au: Yan-Ni Shi Fang-Fang Liu Jacob, Melissa R. Xing-Cong Li Hong-Tao Zhu Dong Wang Rong-Rong Cheng Chong-Ren Yang Min Xu Ying-Jun Zhang affil: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People's Republic of China sug: subj: Candida Alkaloids Analysis Amides Alkaloids Cryptococcus X-Rays Medicine, Chinese Traditional Molecular Structure Plant Extracts ab: Sixty-three amide alkaloids, including three new, piperflaviflorine A (1), piperflaviflorine B (2), and sarmentamide D (4), and two previously synthesized ones, (1 E,3S)-1-cinnamoyl-3-hydroxypyrrolidine (3) and N-[7'-(4'-methoxyphenyl)ethyl]-2-methoxybenzamide (5), were isolated from the aerial parts of Piper flaviflorum and Piper sarmentosum. Their structures were elucidated by detailed spectroscopic analysis and, in case of 3, by single-crystal X-ray diffraction. Most of the isolates were tested for their antifungal and antibacterial activities. Ten amides (6-15) showed antifungal activity against Cryptococcus neoformans ATCC 90113 with IC50 values in the range between 4.7 and 20.0 µg/mL. pubtype: Periodical doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|