Echocardiographic assessment of right ventricular contractile reserve in healthy subjects.
Background Exercise-induced increase in pulmonary artery systolic pressure ( PASP) as a possible measure of right ventricular ( RV) contractile reserve has been shown to predict survival in severe pulmonary hypertension. However, RV contractile reserve can also be measured by changes in stroke volum...
| Publicado en: | Echocardiography Vol. 34; no. 1; pp. 61 - 69 |
|---|---|
| Autores principales: | , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Jan2017
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=120845909&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 120845909 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 07422822 GSE jtl: Echocardiography issn: 07422822 maglogo: Y pubinfo: dt: Jan2017 vid: 34 iid: 1 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 120845909 120845909 120845909 10.1111/echo.13396 120845909 ppf: 61 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Echocardiographic assessment of right ventricular contractile reserve in healthy subjects. aug: au: D'Alto, Michele Pavelescu, Adriana Argiento, Paola Romeo, Emanuele Correra, Anna Di Marco, Giovanni Maria D'Andrea, Antonello Sarubbi, Berardo Russo, Maria Giovanna Naeije, Robert affil: Department of Cardiology, Second University of Naples—Monaldi Hospital, Naples Italy sug: subj: Echocardiography, Doppler, Pulsed Ventricular Function, Right Hypertension, Pulmonary Exercise Test, Cardiopulmonary Human Prospective Studies Male Female Adult Middle Age Work Capacity Evaluation Belgium Italy Electrocardiography Sphygmomanometers Interrater Reliability Intrarater Reliability Descriptive Statistics Data Analysis Software Random Sample Signal Processing, Computer Assisted Pearson's Correlation Coefficient Two-Tailed Test Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Background Exercise-induced increase in pulmonary artery systolic pressure ( PASP) as a possible measure of right ventricular ( RV) contractile reserve has been shown to predict survival in severe pulmonary hypertension. However, RV contractile reserve can also be measured by changes in stroke volume ( SV), tricuspid annular plane systolic excursion ( TAPSE), or tricuspid annular systolic velocity (S'). The limits of normal values and the functional significance of these changes in healthy subjects are not well known. Methods In this prospective study, 90 healthy subjects (45 male, mean age 39 ± 13 years) underwent exercise stress echocardiography with measurement of TAPSE, S', TAPSE/ PASP, SV, and PASP at rest and peak exercise. Maximum and minimum normal values were reported for all indices. Results Normal values of exercise-induced changes (Δ) were 4 to 10 mm for TAPSE, 6 to 14 cm/s for S', 12 to 57 mm Hg for PASP, 0 to 96 mL for SV, and −1.2 to 0 mm/mm Hg for TAPSE/ PASP. At peak exercise, women showed lower Δ TAPSE/ PASP, Δ PASP, ΔS', and Δ SV, but higher TAPSE/ PASP than men. Aging was associated with decreased Δ TAPSE/ PASP, Δ TAPSE, ΔS', Δ PASP, and Δ SV. In addition, ΔS', Δ TAPSE/ PASP, Δ PASP, and Δ SV, but not Δ TAPSE, were directly correlated with maximum workload. Conclusions Our results provide age- and sex-related limits of normal for RV contractile reserve as assessed by exercise stress echocardiography and demonstrate that RV systolic function indices ( PASP, TAPSE, S', and TAPSE/ PASP) correlate with maximum exercise capacity. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|