High-Throughput Classification of Radiographs Using Deep Convolutional Neural Networks.

The study aimed to determine if computer vision techniques rooted in deep learning can use a small set of radiographs to perform clinically relevant image classification with high fidelity. One thousand eight hundred eighty-five chest radiographs on 909 patients obtained between January 2013 and Jul...

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Publicado en:Journal of Digital Imaging Vol. 30; no. 1; pp. 95 - 102
Autores principales: Rajkomar, Alvin, Lingam, Sneha, Taylor, Andrew, Blum, Michael, Mongan, John
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Feb2017
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: High-Throughput Classification of Radiographs Using Deep Convolutional Neural Networks.
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          Rajkomar, Alvin
          Lingam, Sneha
          Taylor, Andrew
          Blum, Michael
          Mongan, John
        affil: Center for Digital Health Innovation , University of California, San Francisco , San Francisco USA
      sug:
        subj:
          Radiography, Thoracic
          Classification
          Image Processing, Computer Assisted
          Neural Networks (Computer) Utilization
          Software
          Human
          Female
          Male
          Confidence Intervals
          Retrospective Design
          Academic Medical Centers California
          California
          Female
          Male
      ab: The study aimed to determine if computer vision techniques rooted in deep learning can use a small set of radiographs to perform clinically relevant image classification with high fidelity. One thousand eight hundred eighty-five chest radiographs on 909 patients obtained between January 2013 and July 2015 at our institution were retrieved and anonymized. The source images were manually annotated as frontal or lateral and randomly divided into training, validation, and test sets. Training and validation sets were augmented to over 150,000 images using standard image manipulations. We then pre-trained a series of deep convolutional networks based on the open-source GoogLeNet with various transformations of the open-source ImageNet (non-radiology) images. These trained networks were then fine-tuned using the original and augmented radiology images. The model with highest validation accuracy was applied to our institutional test set and a publicly available set. Accuracy was assessed by using the Youden Index to set a binary cutoff for frontal or lateral classification. This retrospective study was IRB approved prior to initiation. A network pre-trained on 1.2 million greyscale ImageNet images and fine-tuned on augmented radiographs was chosen. The binary classification method correctly classified 100 % (95 % CI 99.73-100 %) of both our test set and the publicly available images. Classification was rapid, at 38 images per second. A deep convolutional neural network created using non-radiological images, and an augmented set of radiographs is effective in highly accurate classification of chest radiograph view type and is a feasible, rapid method for high-throughput annotation.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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