Cognitive function and its relationship to other psychosocial factors in lymphoma survivors.

Purpose: The purpose of this study was to estimate the prevalence of cognitive disturbance in lymphoma survivors and to explore relationships between cognitive function and other psychosocial factors.Methods: A package of standardized questionnaires was sent to 622 lymphoma patients treated at the O...

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Publicado en:Supportive Care in Cancer Vol. 25; no. 3; pp. 905 - 914
Autores principales: Krolak, Dorothy, Collins, Barbara, Weiss, Lorelle, Harris, Cheryl, Van der Jagt, Richard
Formato: research tables/charts Journal Article
Publicado: Springer Nature Mar2017
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2017
      vid: 25
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      pub: Springer Nature
      place: New York, New York
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        atl: Cognitive function and its relationship to other psychosocial factors in lymphoma survivors.
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        au:
          Krolak, Dorothy
          Collins, Barbara
          Weiss, Lorelle
          Harris, Cheryl
          Van der Jagt, Richard
      sug:
        subj:
          Lymphoma Psychosocial Factors
          Survivors Psychosocial Factors
          Cognition Disorders Psychosocial Factors
          Cognition Disorders Diagnosis
          Cognition Disorders Etiology
          Young Adult
          Executive Function
          Anxiety Etiology
          Anxiety Psychosocial Factors
          Male
          Neuropsychological Tests
          Adult
          Female
          Fatigue Psychosocial Factors
          Fatigue Etiology
          Middle Age
          Aged
          Human
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Purpose: The purpose of this study was to estimate the prevalence of cognitive disturbance in lymphoma survivors and to explore relationships between cognitive function and other psychosocial factors.Methods: A package of standardized questionnaires was sent to 622 lymphoma patients treated at the Ottawa Hospital in the preceding 5 years. Patients with central nervous system involvement were excluded. The questionnaires addressed cognitive function, pain, insomnia, fatigue, and mood. Of the patients in the sampling frame, 54 % responded to the survey and 42 % met inclusion/exclusion criteria. Sixteen percent (99/622) agreed to undergo computerized neuropsychological testing with CNS vital signs (CNSVS). Scores on the objective and subjective cognitive measures were compared to those of a healthy female control group from a previous study.Results: The lymphoma group scored significantly lower than the controls on a cognitive rating scale (p = .018) and on CNSVS (p = .035). The difference on the CNSVS was primarily due to poorer attention and executive function scores in the lymphoma patients. The patients also had a higher frequency of impairment on both the objective (p = .009) and subjective (p < .001) cognitive measures. Among the lymphoma survivors, fatigue and anxiety were related to subjective cognitive disturbance (p < .001 for both), whereas pain was the only psychosocial measure associated with objective cognitive performance (p < .001).Conclusions: These results suggest that cognitive disturbance may be a significant survivorship issue for lymphoma patients and should be more thoroughly investigated in this population.
      pubtype: Academic Journal
      doctype:
        research
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      ougenre: Article
    language: English
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