Simulation of Mental Disorders: II. Computer Models, Purposes and Future Directions.

The complexity of the human brain and the difficulties in identifying and dissecting the biological, social and contextual underpinnings of mental functions confound the study of the etiology and pathophysiology of mental disorders. Simulating mental disorders in animal models or in computer program...

Descripción completa

Detalles Bibliográficos
Publicado en:Israel Journal of Psychiatry & Related Sciences Vol. 53; no. 2; pp. 73 - 82
Autores principales: Gold, Azgad, Dudai, Yadin
Formato: review tables/charts Journal Article
Publicado: Israel Psychiatric Association 2016
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=121025456&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 121025456
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        03337308
        DJ0
      jtl: Israel Journal of Psychiatry & Related Sciences
      issn: 03337308
      maglogo: N
    pubinfo:
      dt: 2016
      vid: 53
      iid: 2
      pid: 68007
      pub: Israel Psychiatric Association
      place: , <Blank>
    artinfo:
      ui:
        121025456
        121025456
        NLM28079040
        121025456
        NLM28079040
        121025456
      ppf: 73
      ppct: 9
      formats:
      tig:
        atl: Simulation of Mental Disorders: II. Computer Models, Purposes and Future Directions.
      aug:
        au:
          Gold, Azgad
          Dudai, Yadin
        affil: Beer Ya'akov Mental Health Center, Beer Ya'akov, Israel.
      sug:
        subj:
          Computer Simulation
          Mental Disorders
      ab: The complexity of the human brain and the difficulties in identifying and dissecting the biological, social and contextual underpinnings of mental functions confound the study of the etiology and pathophysiology of mental disorders. Simulating mental disorders in animal models or in computer programs may contribute to the understanding of such disorders. In the companion paper (30), we discussed selected concepts and pragmatics pertaining to mental illness simulation in general, and then focused on issues pertaining to animal models of mental disease. In this paper, we focus on selected aspects of the merits and limitations of the use of large scale computer simulation in investigating mental disorders. We argue that at the current state of knowledge, the biological-phenomenological gap in understanding mental disorders markedly limits the ability to generate high-fidelity computational models of mental illness. We conclude that similarly to the animal model approach, brain simulation focusing on limited realistic objectives, such as mimicking the emergence of selected distinct attributes of specific mental symptoms in a virtual brain or parts thereof, may serve as a useful tool in exploring mental disorders.
      pubtype: Academic Journal
      doctype:
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N