Vitamin D Deficiency Is Associated with Severity of Acute Coronary Syndrome in Patients with Type 2 Diabetes and High Rates of Sun Exposure.
BACKGROUND: Vitamin D deficiency has been associated with cardiovascular risk factors, including type 2 diabetes mellitus (T2DM). Evidence shows that patients with low serum 25-hydroxyvitamin D (25OHD) concentrations have a higher risk of developing coronary artery disease. OBJECTIVE: The objective...
| Publicado en: | Clinical Medicine Insights: Endocrinology & Diabetes no. 9; pp. 37 - 42 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=121030205&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 121030205 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 11795514 B3KQ jtl: Clinical Medicine Insights: Endocrinology & Diabetes issn: 11795514 maglogo: Y pubinfo: dt: 2016 iid: 9 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 121030205 121030205 121030205 10.4137/CMED.S39427 121030205 ppf: 37 ppct: 5 formats: fmt: @attributes: type: P tig: atl: Vitamin D Deficiency Is Associated with Severity of Acute Coronary Syndrome in Patients with Type 2 Diabetes and High Rates of Sun Exposure. aug: au: Gondim, Fernando Caribé, Ana Ferreira Vasconcelos, Karine Dantas Segundo, Alexandre Bandeira, Francisco affil: Division of Endocrinology, Diabetes, Agamenon Magalhães Hospital, University of Pernambuco Medical School, Recife, Brazil sug: subj: Vitamin D Deficiency Diabetes Mellitus, Type 2 Acute Coronary Syndrome Cardiac Patients Acute Coronary Syndrome Mortality Multiple Logistic Regression Pearson's Correlation Coefficient Fisher's Exact Test Confidence Intervals Descriptive Statistics Odds Ratio Prospective Studies Analysis of Variance Sensitivity and Specificity Probability Validity ab: BACKGROUND: Vitamin D deficiency has been associated with cardiovascular risk factors, including type 2 diabetes mellitus (T2DM). Evidence shows that patients with low serum 25-hydroxyvitamin D (25OHD) concentrations have a higher risk of developing coronary artery disease. OBJECTIVE: The objective of this study was to assess vitamin D as a predictor of the severity in diabetics with acute coronary syndrome (ACS). METHODS: A total of 166 patients were diagnosed with ACS. Serum 25OHD concentrations were analyzed, and risk factors for ACS were evaluated. RESULTS: Patients diagnosed as having acute myocardial infarction with elevation of the ST segment had a higher rate of 25OHD, ,20 ng/mL compared to $30 ng/mL (47.8% × 13.4%, P = 0.03). Diabetics with vitamin D deficiency had more multivessel lesions in the coronary angiography than non-diabetics (69% × 31.8%, P = 0.007). After adjustments for confounders, serum 25OHD remained associated with more severe disease. CONCLUSION: Vitamin D deficiency is associated with more severe ACS and is a predictor of more extensive coronary lesions in patients with T2DM. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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