A Computer-Aided Analysis Method of SPECT Brain Images for Quantitative Treatment Monitoring: Performance Evaluations and Clinical Applications.
The objective and quantitative analysis of longitudinal single photon emission computed tomography (SPECT) images are significant for the treatment monitoring of brain disorders. Therefore, a computer aided analysis (CAA) method is introduced to extract a change-rate map (CRM) as a parametric image...
| Publicado en: | BioMed Research International Vol. 2017; pp. 1 - 12 |
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| Autores principales: | , , , , , |
| Formato: | diagnostic images equations & formulas research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
1/31/2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=121060662&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 121060662 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 1/31/2017 vid: 2017 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 121060662 121060662 121060662 10.1155/2017/1962181 121060662 ppf: 1 ppct: 11 formats: fmt: @attributes: type: P tig: atl: A Computer-Aided Analysis Method of SPECT Brain Images for Quantitative Treatment Monitoring: Performance Evaluations and Clinical Applications. aug: au: Xiujuan Zheng Wentao Wei Qiu Huang Shaoli Song Jieqing Wan Gang Huang affil: Department of Automation, The School of Electrical Engineering Information, Sichuan University, Chengdu, China sug: subj: Carotid Stenosis Therapy Tomography, Emission-Computed, Single-Photon Utilization Cerebrovascular Circulation Evaluation Brain Mapping Methods Cerebral Ischemia Therapy Human Data Collection, Computer Assisted Prospective Studies Algorithms Stents Radioisotopes Male Female Middle Age Aged One-Way Analysis of Variance McNemar's Test Funding Source Middle Aged: 45-64 years Aged: 65+ years Male Female ab: The objective and quantitative analysis of longitudinal single photon emission computed tomography (SPECT) images are significant for the treatment monitoring of brain disorders. Therefore, a computer aided analysis (CAA) method is introduced to extract a change-rate map (CRM) as a parametric image for quantifying the changes of regional cerebral blood flow (rCBF) in longitudinal SPECT brain images. The performances of the CAA-CRM approach in treatment monitoring are evaluated by the computer simulations and clinical applications. The results of computer simulations show that the derived CRMs have high similarities with their ground truths when the lesion size is larger than system spatial resolution and the change rate is higher than 20%. In clinical applications, the CAA-CRM approach is used to assess the treatment of 50 patients with brain ischemia. The results demonstrate that CAA-CRM approach has a 93.4% accuracy of recovered region's localization. Moreover, the quantitative indexes of recovered regions derived fromCRM are all significantly different among the groups and highly correlated with the experienced clinical diagnosis. In conclusion, the proposed CAA-CRM approach provides a convenient solution to generate a parametric image and derive the quantitative indexes from the longitudinal SPECT brain images for treatment monitoring. pubtype: Academic Journal doctype: diagnostic images equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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