The challenge of measuring intra-individual change in fatigue during cancer treatment.

Purpose: To evaluate how well three different patient-reported outcomes (PROs) measure individual change.Methods: Two hundred and fourteen patients (from two sites) initiating first or new chemotherapy for any stage of breast or gastrointestinal cancer participated. The 13-item FACIT Fatigue scale,...

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Publicado en:Quality of Life Research Vol. 26; no. 2; pp. 259 - 272
Autores principales: Moinpour, Carol, Donaldson, Gary, Davis, Kimberly, Potosky, Arnold, Jensen, Roxanne, Gralow, Julie, Back, Anthony, Hwang, Jimmy, Yoon, Jihye, Bernard, Debra, Loeffler, Deena, Rothrock, Nan, Hays, Ron, Reeve, Bryce, Smith, Ashley, Hahn, Elizabeth, Cella, David, Moinpour, Carol M, Donaldson, Gary W, Davis, Kimberly M
Formato: research Journal Article
Publicado: Springer Nature Feb2017
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: The challenge of measuring intra-individual change in fatigue during cancer treatment.
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        au:
          Moinpour, Carol
          Donaldson, Gary
          Davis, Kimberly
          Potosky, Arnold
          Jensen, Roxanne
          Gralow, Julie
          Back, Anthony
          Hwang, Jimmy
          Yoon, Jihye
          Bernard, Debra
          Loeffler, Deena
          Rothrock, Nan
          Hays, Ron
          Reeve, Bryce
          Smith, Ashley
          Hahn, Elizabeth
          Cella, David
          Moinpour, Carol M
          Donaldson, Gary W
          Davis, Kimberly M
        affil: Public Health Sciences Division , Fred Hutchinson Cancer Research Center [Emerita] , Seattle USA
      sug:
        subj:
          Neoplasms Complications
          Fatigue Psychosocial Factors
          Quality of Life Psychosocial Factors
          Middle Age
          Female
          Funding Source
          Scales
          Middle Aged: 45-64 years
          Female
      ab: Purpose: To evaluate how well three different patient-reported outcomes (PROs) measure individual change.Methods: Two hundred and fourteen patients (from two sites) initiating first or new chemotherapy for any stage of breast or gastrointestinal cancer participated. The 13-item FACIT Fatigue scale, a 7-item PROMIS® Fatigue Short Form (PROMIS 7a), and the PROMIS® Fatigue computer adaptive test (CAT) were administered monthly online for 6 months. Reliability of measured change was defined, under a population mixed effects model, as the ratio of estimated systematic variance in rate of change to the estimated total variance of measured individual differences in rate of change. Precision of individual measured change, the standard error of measurement of change, was given by the square root of the rate-of-change sampling variance. Linear and quadratic models were examined up to 3 and up to 6 months.Results: A linear model for measured change showed the following by 6 and 3 months, respectively: PROMIS CAT (0.363 and 0.342); PROMIS SF (0.408 and 0.533); FACIT (0.459 and 0.473). Quadratic models offered no noteworthy improvement over linear models. Both reliability and precision results demonstrate the need to improve the measurement of intra-individual change.Conclusions: These results illustrate the challenge of reliably measuring individual change in fatigue with a level of confidence required for intervention. Optimizing clinically useful measurement of intra-individual differences over time continues to pose a challenge for PROs.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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