Teaming up synthetic chemistry and histochemistry for activity screening in galectin-directed inhibitor design.

A hallmark of endogenous lectins is their ability to select a few distinct glycoconjugates as counterreceptors for functional pairing from the natural abundance of cellular glycoproteins and glycolipids. As a consequence, assays to assess inhibition of lectin binding should necessarily come as close...

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Detalles Bibliográficos
Publicado en:Histochemistry & Cell Biology Vol. 147; no. 2; pp. 285 - 302
Autores principales: Roy, René, Cao, Yihong, Kaltner, Herbert, Kottari, Naresh, Shiao, Tze, Belkhadem, Karima, André, Sabine, Manning, Joachim, Murphy, Paul, Gabius, Hans-Joachim
Formato: Journal Article
Publicado: Springer Nature Feb2017
Acceso en línea:Ver este registro en EBSCOhost