Helicobacter pylori serology testing is a useful diagnostic screening tool for symptomatic inner city children.
Aim: This study assessed the Helicobacter pylori (H. pylori) serum antibody test as a diagnostic screening tool in symptomatic inner city children.Methods: This was a retrospective study of patients aged one to 18 years who were referred to our paediatric gastroenterology department from 2009 to 201...
| Publicado en: | Acta Paediatrica Vol. 106; no. 3; pp. 470 - 478 |
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| Autores principales: | , , |
| Formato: | research Journal Article |
| Publicado: |
Wiley-Blackwell
Mar2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=121235736&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 121235736 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08035253 44C jtl: Acta Paediatrica issn: 08035253 maglogo: Y pubinfo: dt: Mar2017 vid: 106 iid: 3 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 121235736 121235736 NLM28024098 121235736 10.1111/apa.13724 NLM28024098 121235736 ppf: 470 ppct: 8 formats: tig: atl: Helicobacter pylori serology testing is a useful diagnostic screening tool for symptomatic inner city children. aug: au: Raj, Priya Thompson, John F. Pan, Debra H. affil: Division of Gastroenterology Hepatology and Nutrition, The Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx NY, USA sug: subj: Helicobacter Pylori Helicobacter Infections Diagnosis Helicobacter Infections Pathology Adolescence Female Child Feces Helicobacter Infections Blood Human Male Child, Preschool Gastric Mucosa Pathology Urease Analysis Retrospective Design Helicobacter Pylori Immunology Infant Urban Population Validation Studies Comparative Studies Evaluation Research Multicenter Studies Adolescent: 13-18 years Child: 6-12 years Child, Preschool: 2-5 years Infant: 1-23 months Female Male ab: Aim: This study assessed the Helicobacter pylori (H. pylori) serum antibody test as a diagnostic screening tool in symptomatic inner city children.Methods: This was a retrospective study of patients aged one to 18 years who were referred to our paediatric gastroenterology department from 2009 to 2013. We included all patients who had H. pylori serum antibodies and/or faecal antigens who underwent esophagogastroduodenoscopy (EGD) for histology, with or without a gastric tissue rapid urease test.Results: A total of 395 patients had EGDs carried out to evaluate epigastric pain, heartburn and nausea or vomiting, and their overall socio-economic Z-score was -2.62. The histology was positive for H. pylori infection in 52 of 395 patients (13%), and epigastric pain was documented in 45 of these 52 patients (87%). Compared to histology, the serum H. pylori antibody test had a sensitivity of 88.4% and a specificity of 93.4%. The tissue rapid urease test and faecal antigen test had sensitivities of 89.3% and 55.6% and specificities of 89.9% and 98.9%, respectively.Conclusion: The serum H. pylori antibody test had high sensitivity and specificity, and it was a good diagnostic screening tool in our study. Epigastric pain was strongly associated with a current H. pylori infection in our population. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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