Are gastric hyperplastic polyps an additional manifestation in celiac disease?: Results from a retrospective study.

Gastric polyps are frequently reported in patients undergoing upper endoscopic procedures. In this retrospective study, the association between hyperplastic polyps and celiac disease in Northern Sardinia was estimated.Age, gender, body mass index, and medications taken in the 2 preceding months, inc...

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Publicado en:Medicine Vol. 96; no. 5; pp. 1 - 7
Autores principales: Dore, Maria Pina, Pes, Giovanni Mario, Rocchi, Chiara, Loria, Maria Francesca, Soro, Sara, Bassotti, Gabrio
Formato: pictorial research tables/charts Journal Article
Publicado: Lippincott Williams & Wilkins 2/3/2017
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2/3/2017
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      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        atl: Are gastric hyperplastic polyps an additional manifestation in celiac disease?: Results from a retrospective study.
      aug:
        au:
          Dore, Maria Pina
          Pes, Giovanni Mario
          Rocchi, Chiara
          Loria, Maria Francesca
          Soro, Sara
          Bassotti, Gabrio
        affil: Dipartimento di Medicina Clinica e Sperimentale, Clinica Medica, Viale San Pietro, Sassari, University of Sassari, Italy
      sug:
        subj:
          Stomach Neoplasms Epidemiology
          Adenomatous Polyps Epidemiology
          Celiac Disease Epidemiology
          Stomach Neoplasms Pathology
          Adenomatous Polyps Pathology
          Adult
          Middle Age
          Male
          Sex Factors
          Aged
          Retrospective Design
          Endoscopy, Digestive System
          Helicobacter Infections Epidemiology
          Body Mass Index
          Female
          Italy
          Age Factors
          Gastrointestinal Agents Administration and Dosage
          Human
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Gastric polyps are frequently reported in patients undergoing upper endoscopic procedures. In this retrospective study, the association between hyperplastic polyps and celiac disease in Northern Sardinia was estimated.Age, gender, body mass index, and medications taken in the 2 preceding months, including proton-pump inhibitors (PPIs), H2 receptor blockers (anti-H2), Helicobacter pylori status, endoscopic findings, and histology from charts of patients undergoing esophago-gastro-duodenoscopy were reviewed. Polyps were classified as hyperplastic, fundic gland, inflammatory, and adenomatous.3.7% (423/11379) patients had celiac disease. Prevalence of gastric polyps was 4.2% (3.8% among celiac vs 4.2% nonceliac patients). Inflammatory polyp was the most common histotype (55.8% and 56.2%) followed by fundic gland polyps (31.4% and 43.7%), hyperplastic (8.7% and 0%), and adenomas, in celiac and nonceliac patients, respectively. Fundic gland polyps were more common in PPI users (odds ratio: 4.06) than in nonusers (2.65, P = 0.001) among celiac and nonceliac patients. Age older than 50, female gender, esophago-gastro-duodenoscopy year, and PPI use were associated with the presence of polyps, whereas active H pylori infection was not.Gastric polyps were common in Sardinian patients undergoing esophago-gastro-duodenoscopy. However, the previously reported association between hyperplastic polyps and celiac disease was not confirmed in our study.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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