Usefulness of combined use of contrast-enhanced ultrasound and TI-RADS classification for the differentiation of benign from malignant lesions of thyroid nodules.

Purpose: To study the thyroid image reporting and data system (TI-RADS) classification and the contrast-enhanced ultrasound (CEUS) enhancement pattern of thyroid nodules, and to determine whether combined use of both methods is helpful in the diagnosis of thyroid nodules.Methods: A total of 319 thyr...

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Publicado en:European Radiology Vol. 27; no. 4; pp. 1527 - 1537
Autores principales: Zhang, Yan, Zhou, Ping, Tian, Shuang-Ming, Zhao, Yong-Feng, Li, Jia-Le, Li, Lan
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Springer Nature Apr2017
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Usefulness of combined use of contrast-enhanced ultrasound and TI-RADS classification for the differentiation of benign from malignant lesions of thyroid nodules.
      aug:
        au:
          Zhang, Yan
          Zhou, Ping
          Tian, Shuang-Ming
          Zhao, Yong-Feng
          Li, Jia-Le
          Li, Lan
        affil: Department of Ultrasound, The Third Xiangya Hospital , Central South University , Changsha 410013 China
      sug:
        subj:
          Contrast Media
          Ultrasonography Methods
          Radiology Information Systems
          Thyroid Nodule
          Image Enhancement Methods
          Young Adult
          Thyroid Gland
          Adult
          Aged
          Diagnosis, Differential
          Sensitivity and Specificity
          Thyroid Nodule Pathology
          Reproducibility of Results
          Male
          Middle Age
          Female
          Human
          Adult: 19-44 years
          Aged: 65+ years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Purpose: To study the thyroid image reporting and data system (TI-RADS) classification and the contrast-enhanced ultrasound (CEUS) enhancement pattern of thyroid nodules, and to determine whether combined use of both methods is helpful in the diagnosis of thyroid nodules.Methods: A total of 319 thyroid nodules in 246 patients were assessed with TI-RADS, CEUS and a combination of both methods. The diagnostic performance of TI-RADS, CEUS and a combination of both methods was compared.Results: The accuracy in the diagnosis of thyroid nodules was 90.3 % for TI-RADS, 90.0 % for CEUS and 96.0 % for a combination of both methods respectively. A statistically significant difference was not observed in the diagnostic accuracy of CEUS and TI-RADS (P > 0.05). However, a significant difference was observed between a combination of both methods and either alone (P < 0.01). A combination of both methods showed high sensitivity, specificity and accuracy for TI-RADS classifications of 4a and 4b thyroid nodules compared with TI-RADS alone (P < 0.01) and a statistically significant difference was not observed for thyroid nodules classified as 2, 3, and 5 (P > 0.05).Conclusions: The improved TI-RADS, when combined with CEUS, could significantly improve the diagnostic accuracy for thyroid nodules, especially for TI-RADS class-4 thyroid nodules.Key Points: • TI-RADS can be used as the primary diagnostic standard for thyroid nodules • CEUS can be used as an important complement to TI-RADS • The improved TI-RADS can significantly improve the qualitative diagnostic accuracy.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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