Neuroimaging findings of congenital Zika virus infection: a pictorial essay.

Zika virus (ZIKV) is a mosquito-borne arbovirus from the Flaviviridae family. It had caused several epidemics since its discovery in 1947, but there was no significant attention to this virus until the recent outbreak in Brazil in 2015. The main concern is the causal relationship between prenatal ZI...

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Publicado en:Japanese Journal of Radiology Vol. 35; no. 3; pp. 89 - 95
Autores principales: Zare Mehrjardi, Mohammad, Poretti, Andrea, Huisman, Thierry, Werner, Heron, Keshavarz, Elham, Araujo Júnior, Edward, Huisman, Thierry A G M
Formato: Journal Article
Publicado: Springer Nature Mar2017
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Neuroimaging findings of congenital Zika virus infection: a pictorial essay.
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          Zare Mehrjardi, Mohammad
          Poretti, Andrea
          Huisman, Thierry
          Werner, Heron
          Keshavarz, Elham
          Araujo Júnior, Edward
          Huisman, Thierry A G M
          Araujo Júnior, Edward
        affil: Department of Radiology, Shohada Tajrish Hospital , Shahid Beheshti University of Medical Sciences , Tehran Iran
      sug:
        subj:
          Craniofacial Abnormalities
          Neuroradiography Methods
      ab: Zika virus (ZIKV) is a mosquito-borne arbovirus from the Flaviviridae family. It had caused several epidemics since its discovery in 1947, but there was no significant attention to this virus until the recent outbreak in Brazil in 2015. The main concern is the causal relationship between prenatal ZIKV infection and congenital microcephaly, which has been confirmed recently. Moreover, ZIKV may cause other central nervous system abnormalities such as brain parenchymal atrophy with secondary ventriculomegaly, intracranial calcification, malformations of cortical development (such as polymicrogyria, and lissencephaly-pachygyria), agenesis/hypoplasia of the corpus callosum, cerebellar and brainstem hypoplasia, sensorineural hearing-loss, and ocular abnormalities as well as arthrogryposis in the infected fetuses. Postnatal (acquired) ZIKV infection usually has an asymptomatic or mildly symptomatic course, while prenatal (congenital) ZIKV infection has a more severe course and may cause severe brain anomalies that are described as congenital Zika syndrome. In this pictorial essay, we aim to illustrate the prenatal and postnatal neuroimaging findings that may be seen in fetuses and neonates with congenital Zika syndrome, and will discuss possible radiological differential diagnoses. A detailed knowledge of these findings is paramount for an early correct diagnosis, prognosis determination, and counseling of the affected children and families.
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    language: English
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