Development of a DsRed-expressing HepaRG cell line for real-time monitoring of hepatocyte-like cell differentiation by fluorescence imaging, with application in screening of novel geometric microstructured cell growth substrates.
The bipotent nature of the HepaRG cell line is a unique property among human hepatoma-derived cells. Cell treatment with specific differentiation inducers results in a mixture of hepatocyte- and biliary-like cells, accompanied by upregulation of liver-specific proteins, drug metabolizing enzymes, tr...
| Published in: | Biomedical Microdevices Vol. 19; no. 1; pp. 1 - 10 |
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| Main Authors: | , , , , |
| Format: | Journal Article |
| Published: |
Springer Nature
Mar2017
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| Online Access: | View this record in EBSCOhost |