Mechanistic Insight of Probiotics Derived Anticancer Pharmaceuticals: A Road Forward for Cancer Therapeutics.

Probiotics are living organisms that confer health benefits when administered in adequate amounts. Probiotics are continuously being explored for their different health beneficiary activities. Anticancer activity is one of the most important benefits both from a preventive and therapeutic point of v...

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Publicado en:Nutrition & Cancer Vol. 69; no. 3; pp. 375 - 381
Autores principales: Kumar, Raman, Dhanda, Suman
Formato: research Journal Article
Publicado: Taylor & Francis Ltd Apr2017
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Taylor & Francis Ltd
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        10.1080/01635581.2017.1267773
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        atl: Mechanistic Insight of Probiotics Derived Anticancer Pharmaceuticals: A Road Forward for Cancer Therapeutics.
      aug:
        au:
          Kumar, Raman
          Dhanda, Suman
        affil: Department of Biochemistry, Kurukshetra University, Kurukshetra, India
      sug:
        subj:
          Keratolytic Agents
          Probiotics Therapeutic Use
          Problem Solving
          Neoplasms Prevention and Control
          Neoplasms Therapy
          Colonic Neoplasms Prevention and Control
          Inflammatory Bowel Diseases Therapy
          Irritable Bowel Syndrome Therapy
          Animal Studies
          Rats
          In Vivo Studies
          Immune System
      ab: Probiotics are living organisms that confer health benefits when administered in adequate amounts. Probiotics are continuously being explored for their different health beneficiary activities. Anticancer activity is one of the most important benefits both from a preventive and therapeutic point of view. Though not many studies have been conducted to date in this area, a number suggest using laboratory animal models and different cell lines that there may be a mechanistic basis for the anticancer effects of probiotics and require more scientific justification and clinical trials. Most studies of probiotics are conducted for colon cancer associated with inflammatory bowel disease. Studies are also being extended to other types of cancer in different cell lines. This review summarizes studied probiotics considered for treatment of colon cancer and some other cancers (in cancer cell lines) and also proposed mechanism how probiotics are inhibiting cancer growth along with some challenges and future perspectives.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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