Evaluation of the optic nerve using strain and shear wave elastography in patients with multiple sclerosis and healthy subjects.
Aims: Our aim was to evaluate the elasticity features of the optic nerve using strain (SE) and shear wave elastography (SWE) in multiple sclerosis (MS) patients in comparison with healthy subjects.Material and Methods: One hundred and seven optic nerves from 54 MS patients and 118 optic nerves from...
| Publicado en: | Medical Ultrasonography Vol. 19; no. 1; pp. 39 - 45 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
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Romanian Society of Ultrasonography in Medicine & Biology
Mar2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=121780064&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 121780064 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18444172 AX1S jtl: Medical Ultrasonography issn: 18444172 maglogo: N pubinfo: dt: Mar2017 vid: 19 iid: 1 pid: 57537 pub: Romanian Society of Ultrasonography in Medicine & Biology artinfo: ui: 121780064 121780064 NLM28180195 10.11152/mu-939 NLM28180195 121780064 ppf: 39 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Evaluation of the optic nerve using strain and shear wave elastography in patients with multiple sclerosis and healthy subjects. aug: au: İnal, Mikail Tan, Sinan Yumusak, M. Erhan Şahan, Mehmet Hamdi Alpua, Murat Örnek, Kemal Yumusak, Erhan M affil: Department of Radiology, Kirikkale University Faculty of Medicine, Kirikkale, Turkey sug: subj: Multiple Sclerosis Physiopathology Optic Nerve Optic Nerve Physiopathology Ultrasonography Methods Sensitivity and Specificity Young Adult Adolescence Adult Middle Age Female Male Arthritis Impact Measurement Scales Adolescent: 13-18 years Adult: 19-44 years Middle Aged: 45-64 years Female Male ab: Aims: Our aim was to evaluate the elasticity features of the optic nerve using strain (SE) and shear wave elastography (SWE) in multiple sclerosis (MS) patients in comparison with healthy subjects.Material and Methods: One hundred and seven optic nerves from 54 MS patients and 118 optic nerves from 59 healthy subjects were examined prospectively by SE and SWE. Optic nerves were divided into three types in accordance to the elasticity designs, as follows: type 1 predominantly blue (hardest tissue); type 2 predominantly blue/green (hard tissue); and type 3 predominantly green (intermediate tissue). Quantitative measurements of optic nerve hardness with SWE were analyzed in kilopascals.Results: Elastographic images from healthy volunteers showed mostly type 3 optic nerves (61.9%); type 2 was also found (38.1%), but type 1 was not observed. Elastographic examination of MS patients showed mostly type 2 optic nerves (88%), while some type 1 (4.6%) and type 3 optic nerves (6.5%) were rarely observed. There was a statistically significant difference in terms of elasticity patterns between patients and healthy volunteers (p<0.001). Statistically significant differences were observed between patients and healthy volunteers in the analysis of SWE values (10.381±3.48 kPa and 33.87±11.64 p<0.001). The receiver operating characteristic curve analysis was perfect (0.993; 95% confidence interval [CI]=0.971-0.999), and a cut-off value of 18.3 kPa shear had very high sensitivity and specificity for the patient group. No significant differences were observed between patients with and without previous optic neuritis.Conclusion: SE and SWE examination findings concerning the optic nerve in MS patients demonstrated remarkable differences according to the healthy group. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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