Noninvasive quantitative estimation of hepatic steatosis by ultrasound: a comparison of the hepato-renal index and ultrasound attenuation index.
Aims: To compare the accuracy of the ultrasound attenuation index (USAI) and hepato-renal index (HRI) for the diagnosis of hepatic steatosis (HS).Material and Methods: Two hundred and twenty-four potential living hepatic donors underwent US and subsequent US-guided liver biopsy. The USAI was calcula...
| Publicado en: | Medical Ultrasonography Vol. 18; no. 4; pp. 431 - 438 |
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| Autores principales: | , , , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Romanian Society of Ultrasonography in Medicine & Biology
Dec2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=121787312&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 121787312 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18444172 AX1S jtl: Medical Ultrasonography issn: 18444172 maglogo: N pubinfo: dt: Dec2016 vid: 18 iid: 4 pid: 57537 pub: Romanian Society of Ultrasonography in Medicine & Biology artinfo: ui: 121787312 121787312 NLM27981274 121787312 10.11152/mu-868 NLM27981274 121787312 ppf: 431 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Noninvasive quantitative estimation of hepatic steatosis by ultrasound: a comparison of the hepato-renal index and ultrasound attenuation index. aug: au: Heon-Ju Kwon Kyoung Won Kim Jin-Hee Jung Sang Hyun Choi Woo Kyoung Jeong Bohyun Kim Gi-Won Song Sung-Gyu Lee Kwon, Heon-Ju Kim, Kyoung Won Jung, Jin-Hee Choi, Sang Hyun Jeong, Woo Kyoung Kim, Bohyun Song, Gi-Won Lee, Sung-Gyu affil: Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul sug: subj: Kidney Ultrasonography Methods Nonalcoholic Fatty Liver Disease Liver Image Interpretation, Computer Assisted Methods Nonalcoholic Fatty Liver Disease Physiopathology Female Adult Liver Function Tests Methods Human Reproducibility of Results Sensitivity and Specificity Male Young Adult Middle Age Adolescence Validation Studies Comparative Studies Evaluation Research Multicenter Studies Adult: 19-44 years Middle Aged: 45-64 years Adolescent: 13-18 years Female Male ab: Aims: To compare the accuracy of the ultrasound attenuation index (USAI) and hepato-renal index (HRI) for the diagnosis of hepatic steatosis (HS).Material and Methods: Two hundred and twenty-four potential living hepatic donors underwent US and subsequent US-guided liver biopsy. The USAI was calculated from US images with an 8 MHz transducer and HRI was measured on sagittal images with a clear visualization of both the liver and kidney. Using histological degrees of HS as the reference standard, we compared the performance of USAI and HRI for diagnosing HS ≥ 5% and ≥ 30% by receiver operating characteristic curve analysis. The interobserver agreement was evaluated by using intraclass correlation coefficients (ICCs) or Bland-Altman statistics.Results: Histologic degree of HS was 0-70% (median, 5%). HRI showed a tendency towards higher accuracy than USAI for diagnosing HS ≥ 5% (the area under the ROC curve, 0.856 vs. 0.820; p= 0.279) and ≥ 30% (0.937 vs. 0.909; p = 0.378) without statistical significance. There was an excellent interobserver agreement for both USAI and HRI (ICC = 0.931 and 0.973, respectively). According to the Bland-Altman method, the 95% limits of difference between two readers for HS were -8.5% to 6.6% by USAI and -4.8% to 6.2% by HRI. Most patients would have the difference of calculated HS by USAI (74.0%) and HRI (96.0%) from different operators within a range of ±5%.Conclusions: Although statistically insignificant, HRI was superior to USAI for the diagnosis and quantitative estimation of HS in terms of diagnostic performance, including accuracy and reproducibility. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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