MRI-directed cognitive fusion-guided biopsy of the anterior prostate tumors.
Purpose: We aimed to evaluate the efficacy of magnetic resonance imaging (MRI)-directed cognitive fusion transrectal ultrasonography (TRUS)-guided anterior prostate biopsy for diagnosis of anterior prostate tumors and to illustrate this technique.Methods: A total of 39 patients with previous negativ...
| Publicado en: | Diagnostic & Interventional Radiology Vol. 23; no. 2; pp. 87 - 94 |
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| Autores principales: | , , , |
| Formato: | Journal Article |
| Publicado: |
Galenos Yayinevi Tic. LTD. STI
Mar/Apr2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=121817977&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 121817977 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13053825 39NM jtl: Diagnostic & Interventional Radiology issn: 13053825 maglogo: N pubinfo: dt: Mar/Apr2017 vid: 23 iid: 2 pid: 28155 pub: Galenos Yayinevi Tic. LTD. STI artinfo: ui: 121817977 121817977 NLM28074780 10.5152/dir.2016.15445 NLM28074780 121817977 ppf: 87 ppct: 7 formats: fmt: @attributes: type: P tig: atl: MRI-directed cognitive fusion-guided biopsy of the anterior prostate tumors. aug: au: Murphy, Ian G. NiMhurchu, Elaine Gibney, Robert G. McMahon, Colm J. affil: Department of Radiology, St. Vincent's University Hospital, Dublin Ireland sug: subj: Prostatic Neoplasms Magnetic Resonance Imaging Methods Adenocarcinoma Adenocarcinoma Pathology Prostatic Neoplasms Pathology Prostatic Neoplasms Metabolism Aged Prostate-Specific Antigen Metabolism Logistic Regression Male Middle Age Ultrasonography Sensitivity and Specificity Biopsy Neoplasm Staging Scales Aged: 65+ years Middle Aged: 45-64 years Male ab: Purpose: We aimed to evaluate the efficacy of magnetic resonance imaging (MRI)-directed cognitive fusion transrectal ultrasonography (TRUS)-guided anterior prostate biopsy for diagnosis of anterior prostate tumors and to illustrate this technique.Methods: A total of 39 patients with previous negative TRUS biopsy, but high clinical suspicion of occult prostate cancer, prospectively underwent prostate MRI including diffusion-weighted imaging (DWI). Patients with a suspicious anterior lesion on MRI underwent targeted anterior gland TRUS-guided biopsy with cognitive fusion technique using sagittal probe orientation. PIRADS version 1 scores (T2, DWI, and overall), lesion size, prostate-specific antigen (PSA), PSA density, and prostate gland volume were compared between positive and negative biopsy groups and between clinically significant cancer and remaining cases. Logistic regression analysis of imaging parameters and prostate cancer diagnosis was performed.Results: Anterior gland prostate adenocarcinoma was diagnosed in 18 patients (46.2%) on targeted anterior gland TRUS-guided biopsy. Clinically significant prostate cancer was diagnosed in 13 patients (33.3%). MRI lesion size, T2, DWI, and overall PIRADS scores were significantly higher in patients with positive targeted biopsies and those with clinically significant cancer (P < 0.05). Biopsies were positive in 90%, 33%, and 29% of patients with overall PIRADS scores of 5, 4, and 3 respectively. Overall PIRADS score was an independent predictor of all prostate cancer diagnosis and of clinically significant prostate cancer diagnosis.Conclusion: Targeted anterior gland TRUS-guided biopsy with MRI-directed cognitive fusion enables accurate sampling and may improve tumor detection yield of anterior prostate cancer. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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