Acupuncture for the Treatment of Peripheral Neuropathy: A Systematic Review and Meta-Analysis.
Objectives: Neuropathy and its associated pain pose great therapeutic challenges. While there has been a recent surge in acupuncture use and research, little remains known about its effects on nerve function. This review aims to assess the efficacy of acupuncture in the treatment of neuropathy of va...
| Published in: | Journal of Alternative & Complementary Medicine Vol. 23; no. 3; pp. 164 - 180 |
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| Main Authors: | , , |
| Format: | research systematic review tables/charts Journal Article |
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Mary Ann Liebert, Inc.
Mar2017
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=121839222&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 121839222 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10755535 C1G jtl: Journal of Alternative & Complementary Medicine issn: 10755535 maglogo: N pubinfo: dt: Mar2017 vid: 23 iid: 3 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 121839222 121839222 121839222 10.1089/acm.2016.0155 121839222 ppf: 164 ppct: 16 formats: tig: atl: Acupuncture for the Treatment of Peripheral Neuropathy: A Systematic Review and Meta-Analysis. aug: au: Dimitrova, Alexandra Murchison, Charles Oken, Barry sug: subj: Acupuncture Utilization Peripheral Nervous System Diseases Therapy Treatment Outcomes Patient Safety Human Bell Palsy Carpal Tunnel Syndrome Diabetic Neuropathies Facial Paralysis Systematic Review Medline AMED Database CINAHL Database Cochrane Library Randomized Controlled Trials HIV Infections Descriptive Statistics Confidence Intervals Meta Analysis Odds Ratio Fisher's Exact Test Data Analysis Software Acupuncture Points Funding Source Scales ab: Objectives: Neuropathy and its associated pain pose great therapeutic challenges. While there has been a recent surge in acupuncture use and research, little remains known about its effects on nerve function. This review aims to assess the efficacy of acupuncture in the treatment of neuropathy of various etiologies. Methods: The Medline, AMED, Cochrane, Scopus, CINAHL, and databases were systematically searched from inception to July 2015. Randomized controlled trials (RCTs) assessing acupuncture's efficacy for poly- and mononeuropathy were reviewed. Parallel and crossover RCTs focused on acupuncture's efficacy were reviewed and screened for eligibility. The Scale for Assessing Scientific Quality of Investigations in Complementary and Alternative Medicine was used to assess RCT quality. RCTs with score of >9 and active control treatments such as sham acupuncture or medical therapy were included. Results: Fifteen studies were included: 13 original RCTs, a long-term follow-up, and a re-analysis of a prior RCT. The selected RCTs studied acupuncture for neuropathy caused by diabetes, Bell's palsy, carpal tunnel syndrome, human immunodeficiency virus (HIV), and idiopathic conditions. Acupuncture regimens, control conditions, and outcome measures differed among studies, and various methodological issues were identified. Still, the majority of RCTs showed benefit for acupuncture over control in the treatment of diabetic neuropathy, Bell's palsy, and carpal tunnel syndrome. Acupuncture is probably effective in the treatment of HIV-related neuropathy, and there is insufficient evidence for its benefits in idiopathic neuropathy. Acupuncture appears to improve nerve conduction study parameters in both sensory and motor nerves. Meta-analyses were conducted on all diabetic neuropathy and Bell's palsy individual subject data (six RCTs; a total of 680 subjects) using a summary estimate random effects model, which showed combined odds ratio of 4.23 (95% confidence interval 2.3-7.8; p < 0.001) favoring acupuncture over control for neuropathic symptoms. Conclusions: Acupuncture is beneficial in some peripheral neuropathies, but more rigorously designed studies using sham-acupuncture control are needed to characterize its effect and optimal use better. pubtype: Academic Journal doctype: meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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