A comparative outcomes analysis evaluating clinical effectiveness in two different human placental membrane products for wound management.
Advances in tissue preservation have led to the commercialization of human placental membranes for the purposes of wound management with each product being characterized by different compositions and properties. The a priori specification of the research question in this investigator-initiated study...
| Publicado en: | Wound Repair & Regeneration Vol. 25; no. 1; pp. 145 - 150 |
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| Autores principales: | , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Jan/Feb2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=121992637&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 121992637 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10671927 DPV jtl: Wound Repair & Regeneration issn: 10671927 maglogo: Y pubinfo: dt: Jan/Feb2017 vid: 25 iid: 1 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 121992637 121992637 121992637 10.1111/wrr.12503 121992637 ppf: 145 ppct: 5 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: A comparative outcomes analysis evaluating clinical effectiveness in two different human placental membrane products for wound management. aug: au: Johnson, Eric L. Marshall, James T. Michael, Georgina M. affil: Bozeman Health Deaconess Hospital, Wound and Hyperbaric Center, Bozeman Montana sug: subj: Placenta Biological Dressings Evaluation Wound Healing Wound Care Wounds and Injuries Therapy Treatment Outcomes Clinical Effectiveness Prospective Studies Human Cryopreservation Male Female Middle Age Aged Aged, 80 and Over Body Mass Index Comorbidity Wound Measurement Disease Duration Descriptive Statistics Chi Square Test Fisher's Exact Test T-Tests Outpatient Service Outpatients P-Value Kaplan-Meier Estimator Negative Pressure Wound Therapy Hyperbaric Oxygenation Wounds and Injuries Etiology Wounds and Injuries Classification Wounds and Injuries Prognosis Amnion Chorion Outcomes Research Comparative Studies Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Advances in tissue preservation have led to the commercialization of human placental membranes for the purposes of wound management with each product being characterized by different compositions and properties. The a priori specification of the research question in this investigator-initiated study focused on the clinical outcomes in two nonrandomized, however statistically equal and homogenous patient cohorts receiving either a viable intact cryopreserved human placental membrane (vCPM) or a dehydrated human amnion/chorion membrane (dHACM), for the management of wounds at a single center. A total of 79 patients with 101 wounds were analyzed: 40 patients with 46 wounds received vCPM and 39 patients with 55 wounds received dHACM. The proportion of wounds achieving complete wound closure was 63.0% (29/46) for vCPM and 18.2% (10/55) for dHACM ( p < 0.0001) for all treated wounds combined. This is the first comparative effectiveness study to report on the clinical outcomes associated with the use of different placental wound care products once broadly implemented in the clinical setting. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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