The Combination of Computational and Biosensing Technologies for Selecting Aptamer against Prostate Specific Antigen.

Herein, we report a method of combining bioinformatics and biosensing technologies to select aptamers against prostate specific antigen (PSA). The main objective of this study is to select DNA aptamers with higher binding affinity for PSA by using the proposed method. Based on the five known sequenc...

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Bibliographic Details
Published in:BioMed Research International Vol. 2017; pp. 1 - 12
Main Authors: Hsieh, Pi-Chou, Lin, Hui-Ting, Chen, Wen-Yih, Tsai, Jeffrey J. P., Hu, Wen-Pin
Format: equations & formulas research tables/charts Journal Article
Published: Wiley-Blackwell 3/28/2017
Online Access:View this record in EBSCOhost