Stiffness of benign and malignant prostate tissue measured by shear-wave elastography: a preliminary study.
Objectives: To measure benign and malignant prostate tissue stiffness using shear-wave elastography (SWE).Methods: Thirty consecutive patients underwent transrectal SWE in the axial and sagittal planes before prostatectomy. After reviewing prostatectomy specimens, two radiologists measured stiffness...
| Publicado en: | European Radiology Vol. 27; no. 5; pp. 1858 - 1867 |
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| Autores principales: | , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
May2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=122196897&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 122196897 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: May2017 vid: 27 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 122196897 122196897 143902462 NLM27553936 10.1007/s00330-016-4534-9 NLM27553936 122196897 ppf: 1858 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Stiffness of benign and malignant prostate tissue measured by shear-wave elastography: a preliminary study. aug: au: Rouvière, Olivier Melodelima, Christelle Hoang Dinh, Au Bratan, Flavie Pagnoux, Gaele Sanzalone, Thomas Crouzet, Sébastien Colombel, Marc Mège-Lechevallier, Florence Souchon, Rémi Rouvière, Olivier Crouzet, Sébastien Mège-Lechevallier, Florence Souchon, Rémi affil: Inserm, U1032, LabTau, Lyon 69003 France sug: subj: Prostatic Neoplasms Prostate Prostatic Hypertrophy Aged Prostatic Neoplasms Surgery Prostatic Hypertrophy Surgery Middle Age Prostatic Hypertrophy Blood Prospective Studies Multivariate Analysis Prostate-Specific Antigen Blood Male Prostatic Neoplasms Blood Prostatectomy Ultrasonography Methods Aged: 65+ years Middle Aged: 45-64 years Male ab: Objectives: To measure benign and malignant prostate tissue stiffness using shear-wave elastography (SWE).Methods: Thirty consecutive patients underwent transrectal SWE in the axial and sagittal planes before prostatectomy. After reviewing prostatectomy specimens, two radiologists measured stiffness in regions corresponding to cancers, lateral and median benign peripheral zone (PZ) and benign transition zone (TZ).Results: Cancers were stiffer than benign PZ and TZ. All tissue classes were stiffer on sagittal than on axial imaging, in TZ than in PZ, and in median PZ than in lateral PZ. At multivariate analysis, the nature of tissue (benign or malignant; P < 0.00001), the imaging plane (axial or sagittal; P < 0.00001) and the location within the prostate (TZ, median PZ or lateral PZ; P = 0.0065) significantly and independently influenced tissue stiffness. On axial images, the thresholds maximising the Youden index in TZ, lateral PZ and median PZ were respectively 62 kPa, 33 kPa and 49 kPa. On sagittal images, the thresholds were 76 kPa, 50 kPa and 72 kPa, respectively.Conclusions: SWE can distinguish prostate malignant and benign tissues. Tissue stiffness is influenced by the imaging plane and the location within the gland.Key Points: • Prostate cancers were stiffer than the benign peripheral zone • All tissue classes were stiffer on sagittal than on axial imaging • All tissue classes were stiffer in the transition zone than in the peripheral zone • All tissue classes were stiffer in the median than in the lateral peripheral zone • Taking into account imaging plane and zonal anatomy can improve cancer detection. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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