Effects of increased left ventricular wall thickness on the myocardium in severe aortic stenosis with normal left ventricular ejection fraction: Two- and three-dimensional multilayer speckle tracking echocardiography.
Background The aim of this study was to determine the capability of real time three-dimensional echocardiography ( RT3 DE) and two-dimensional (2D) multilayer speckle tracking echocardiography ( MSTE) for evaluation of early myocardial dysfunction triggered by increased left ventricular ( LV) wall t...
| Publicado en: | Echocardiography Vol. 34; no. 4; pp. 511 - 523 |
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| Autores principales: | , , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Apr2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=122314325&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 122314325 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 07422822 GSE jtl: Echocardiography issn: 07422822 maglogo: Y pubinfo: dt: Apr2017 vid: 34 iid: 4 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 122314325 122314325 122314325 10.1111/echo.13474 122314325 ppf: 511 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Effects of increased left ventricular wall thickness on the myocardium in severe aortic stenosis with normal left ventricular ejection fraction: Two- and three-dimensional multilayer speckle tracking echocardiography. aug: au: Cho, Eun Jeong Park, Sung‐Ji Kim, Eun Kyoung Lee, Ga Yeon Chang, Sung‐A Choi, Jin‐Oh Lee, Sang‐Chol Park, Seung Woo affil: Division of Cardiology, Department of Internal Medicine, Cardiovascular Imaging Center, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul Korea sug: subj: Aortic Valve Stenosis Ventricular Function, Left Ventricular Ejection Fraction Echocardiography Evaluation Human Middle Age Aged Male Female Patient Selection Time Factors Chi Square Test T-Tests Fisher's Exact Test Two-Tailed Test Pearson's Correlation Coefficient Linear Regression Data Analysis Software Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Background The aim of this study was to determine the capability of real time three-dimensional echocardiography ( RT3 DE) and two-dimensional (2D) multilayer speckle tracking echocardiography ( MSTE) for evaluation of early myocardial dysfunction triggered by increased left ventricular ( LV) wall thickness in severe aortic stenosis ( AS) with normal LV ejection fraction ( EF≥55%). Methods Conventional, RT3D STE and 2D MSTE were performed in 45 patients (mean 68.9±9.0 years) with severe AS (aortic valve area <1 cm2, aortic velocity Vmax >4 m/s or mean PG >40 mm Hg) and normal left ventricular ejection fraction ( LVEF) without overt coronary artery disease and in 18 age-, sex-matched healthy controls. Global longitudinal strain ( GLS), global circumferential strain ( GCS), global area strain ( GAS), and global radial strain ( GRS) were calculated using RT3 DE and MSTE. Results The severe AS group had lower 3D GLS, GRS, GAS and 2D epicardium, and mid-wall and endocardium GLS compared to healthy controls. In MSTE analysis, 2D LS and CS values decreased from the endocardial layer toward the epicardial layer. Severe AS patients with increased LV wall thickness had lower 3D GLS and 2D epicardium, and mid-wall and endocardium GLS compared with severe AS patients without LV wall thickening. GLS on RT3D STE was correlated with GLS on 2D MSTE, left ventricular mass index, LVEF, left atrial volume index, and ln NT-pro BNP. Conclusion RT3 DE and 2D MSTE can be used to identify subtle contractile dysfunction triggered by increased LV wall thickness in severe AS with normal LVEF. Therefore, RT3D STE and 2D MSTE may provide additional information that can facilitate decision-making regarding severe AS patients with increased LV wall thickness and normal LV function. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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